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Literature summary extracted from

  • Chrisman, T.D.; Sobo, G.E.; Exton, J.H.
    The Mg2+ requirements of nonactivated and activated rat liver phosphorylase kinase. Inhibition of the activated form by free Mg2+ (1984), FEBS Lett., 167, 295-300.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.19 ATP free ATP, reversible Rattus norvegicus
2.7.11.19 Mg2+ free Mg2+, only activated enzyme, reversible Rattus norvegicus
2.7.11.19 Mn2+ free Mn2+ Rattus norvegicus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.19 Ca2+
-
 Rattus norvegicus
2.7.11.19 Mg2+ requirement Rattus norvegicus
2.7.11.19 Mg2+ 10 mM Rattus norvegicus
2.7.11.19 Mg2+ free Mg2+ inhibits activated enzyme Rattus norvegicus
2.7.11.19 Mg2+ free Mg2+ stimulates (nonactivated enzyme) Rattus norvegicus
2.7.11.19 Mg2+ major role of Mg2+: cosubstrate in Mg2+-ATP complex Rattus norvegicus
2.7.11.19 Mg2+ required for activity phosphorylation by (cAMP-dependent protein kinase) Rattus norvegicus
2.7.11.19 phosphate requirement, phosphate containing enzyme Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.19 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.19 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.19 ATP + phosphorylase b cosubstrate: Mg-ATP complex Rattus norvegicus ADP + phosphorylase a
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.11.19 30
-
 assay at Rattus norvegicus