EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.7.11.19 | Catalytic subunit of cAMP-dependent protein kinase | activation of nonactivated enzyme | Oryctolagus cuniculus | |
2.7.11.19 | Catalytic subunit of cAMP-dependent protein kinase | Mn2+ stimulates | Oryctolagus cuniculus | |
2.7.11.19 | Catalytic subunit of cAMP-dependent protein kinase | subunits, in the presence of ATP and Mg2+ | Oryctolagus cuniculus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.11.19 | (D)-Arg-(D)-Leu-(D)-Ser-(D)-Leu | Ser-Asp-Gln-Glu-Lys-Arg-Lys-Gln-Ile-Ser-Val-Arg-Gly-Leu as substrate | Oryctolagus cuniculus | |
2.7.11.19 | (D)-Leu-(D)-Ser-(D)-Leu-(D)-Arg | - |
Oryctolagus cuniculus | |
2.7.11.19 | (D)-Leu-(D)-Ser-(D)-Tyr-(D)-Arg-(D)-Arg-(D)-Tyr-(D)-Ser-(D)-Leu | - |
Oryctolagus cuniculus | |
2.7.11.19 | Arg-Lys-Gln-Ile-Thr-Val-Arg | synthetic peptides as substrate | Oryctolagus cuniculus | |
2.7.11.19 | Ile-Ser-Val-Arg-Gly | Ser-Asp-Gln-Glu-Lys-Arg-Lys-Gln-Ile-Ser-Val-Arg-Gly-Leu as substrate | Oryctolagus cuniculus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.11.19 | additional information | - |
additional information | kinetic data for phosphorylase b | Oryctolagus cuniculus | |
2.7.11.19 | additional information | - |
additional information | kinetic data for peptides derived from glycogen synthase | Oryctolagus cuniculus | |
2.7.11.19 | 0.2 | 2.3 | peptides | from phosphorylase b, synthetic | Oryctolagus cuniculus | |
2.7.11.19 | 0.27 | - |
phosphorylase b | nonactivated enzyme | Oryctolagus cuniculus | |
2.7.11.19 | 0.7 | 3.5 | peptides | from glycogen synthase, synthetic | Oryctolagus cuniculus |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.7.11.19 | Ca2+ | - |
Oryctolagus cuniculus | |
2.7.11.19 | Mg2+ | requirement | Oryctolagus cuniculus | |
2.7.11.19 | Mg2+ | major role of Mg2+: cosubstrate in Mg2+-ATP complex | Oryctolagus cuniculus | |
2.7.11.19 | Mg2+ | required for activity phosphorylation by (cAMP-dependent protein kinase) | Oryctolagus cuniculus | |
2.7.11.19 | Mn2+ | activation | Oryctolagus cuniculus | |
2.7.11.19 | Mn2+ | stimulates activation by catalytic subunit of cAMP-dependent protein kinase | Oryctolagus cuniculus | |
2.7.11.19 | phosphate | requirement, phosphate containing enzyme | Oryctolagus cuniculus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.11.19 | Oryctolagus cuniculus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.11.19 | skeletal muscle | - |
Oryctolagus cuniculus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.11.19 | ATP + casein | kappa-casein | Oryctolagus cuniculus | ? | - |
? | |
2.7.11.19 | ATP + glycogen synthase | - |
Oryctolagus cuniculus | ADP + phosphoglycogen synthase | - |
? | |
2.7.11.19 | ATP + histone H1 | - |
Oryctolagus cuniculus | ? | - |
? | |
2.7.11.19 | ATP + nonactivated phosphorylase kinase | - |
Oryctolagus cuniculus | ADP + activated phosphorylase kinase | - |
? | |
2.7.11.19 | ATP + phosphorylase b | - |
Oryctolagus cuniculus | ADP + phosphorylase a | - |
? | |
2.7.11.19 | ATP + phosphorylase b | best substrate | Oryctolagus cuniculus | ADP + phosphorylase a | - |
? | |
2.7.11.19 | ATP + phosphorylase b | cosubstrate: Mg-ATP complex | Oryctolagus cuniculus | ADP + phosphorylase a | - |
? | |
2.7.11.19 | ATP + phosphorylase b | rabbit skeletal muscle | Oryctolagus cuniculus | ADP + phosphorylase a | - |
? | |
2.7.11.19 | ATP + phosphorylase b | human, rat | Oryctolagus cuniculus | ADP + phosphorylase a | - |
? | |
2.7.11.19 | ATP + sarcolemmal protein | - |
Oryctolagus cuniculus | ? | - |
? | |
2.7.11.19 | ATP + sarcoplasmic protein | - |
Oryctolagus cuniculus | ? | - |
? | |
2.7.11.19 | ATP + synthetic peptides derived from glycogen synthase | overview, phosphorylation at the same site as glycogen synthase | Oryctolagus cuniculus | ? | - |
? | |
2.7.11.19 | ATP + synthetic peptides derived from phosphorylase b | overview | Oryctolagus cuniculus | ? | - |
? | |
2.7.11.19 | ATP + synthetic tetradecapeptide | i.e. Ser-Asp-Gln-Glu-Lys-Arg-Lys-Gln-Ile-Ser-Val-Arg-Gly-Leu | Oryctolagus cuniculus | ? | - |
? | |
2.7.11.19 | ATP + troponin I | - |
Oryctolagus cuniculus | ADP + phosphotroponin I | - |
? | |
2.7.11.19 | ATP + troponin T | - |
Oryctolagus cuniculus | ADP + phosphotroponin T | - |
? | |
2.7.11.19 | additional information | specificity | Oryctolagus cuniculus | ? | - |
? | |
2.7.11.19 | additional information | Lys-Gln-Ile-Ser-Val-Arg, Ser-Asp-Gln-Glu-Lys-Arg-Lys-Gln-Gly-Ser-Gly-Arg-Gly-Leu, Lys-Gln-Ile-Thr-Val-Arg, Arg-Lys-Gln-Ile-Thr-Val-Arg are no substrates | Oryctolagus cuniculus | ? | - |
? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.7.11.19 | 30 | - |
assay at | Oryctolagus cuniculus |