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Literature summary extracted from

  • Janji, B.; Melchior, C.; Vallar, L.; Kieffer, N.
    Cloning of an isoform of integrin-linked kinase (ILK) that is upregulated in HT-144 melanoma cells following TGF-beta1 stimulation (2000), Oncogene, 19, 3069-3077.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.10.2 ATP + a protein Homo sapiens enzyme is upregulated in HT-144 melanoma cells following TGF-beta1 stimulation ADP + a phosphoprotein
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.10.2 Homo sapiens Q13418
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.10.2 HT-1080 cell metastatic fibrosarcoma cell line Homo sapiens
-
2.7.10.2 HT-144 cell metastatic human melanoma cell line Homo sapiens
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2.7.10.2 additional information no expression in normal human tissues Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.10.2 ATP + a protein autophosphorylation Homo sapiens ADP + a phosphoprotein
-
 ?
2.7.10.2 ATP + a protein enzyme is upregulated in HT-144 melanoma cells following TGF-beta1 stimulation Homo sapiens ADP + a phosphoprotein
-
 ?
2.7.10.2 ATP + beta 1-integrin cytoplasmic domain peptide
-
 Homo sapiens ADP + ?
-
 ?
2.7.10.2 ATP + myelin basic protein
-
 Homo sapiens ADP + ?
-
 ?
2.7.10.2 ATP + recombinant GST/beta3 integrin cytoplasmic tail peptide
-
 Homo sapiens ADP + ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.10.2 integrin-linked protein kinase 76
-
 Homo sapiens