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Literature summary extracted from

  • Gerwins, P.; Blank, J.L.; Johnson, G.L.
    Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway (1997), J. Biol. Chem., 272, 8288-8295.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.11.25
-
 Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.11.25 additional information localized to perinuclear, vesicular compartment similar to the Golgi Mus musculus
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.11.25 180000
-
-
 Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.25 ATP + protein Mus musculus selectively regulates the c-Jun amino terminal kinase pathway ADP + phosphoprotein
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.25 Mus musculus O08648
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.25 ATP + protein selectively regulates the c-Jun amino terminal kinase pathway Mus musculus ADP + phosphoprotein
-
 ?
2.7.11.25 additional information MEKK4 binds to Cdc42 and Rac Mus musculus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.25 mitogen-activated protein kinase kinase kinase 4
-
 Mus musculus