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Literature summary extracted from

  • Zhai, L.; Graves, P.R.; Robinson, L.C.; Italiano, M.; Culbertson, M.R.; Rowles, J.; Cobb, M.H.; DePaoli-Roach, A.A.; Roach, P.J.
    Casein kinase I gamma subfamily. Molecular cloning, expression, and characterization of three mammalian isoforms and complementation of defects in the Saccharomyces cerevisiae YCK genes (1995), J. Biol. Chem., 270, 12717-12724.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.1 heparin activation with peptide substrate Rattus norvegicus

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.11.1 expressed as active enzyme in Escherichia coli Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.1 heparin inhibition with casein and phosvitin as substrate Rattus norvegicus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.1 Mg2+ autophosphorylation when incubated with ATP and Mg2+ Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.11.1 43000
-
-
 Rattus norvegicus
2.7.11.1 45500
-
-
 Rattus norvegicus
2.7.11.1 49700
-
-
 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.1 Rattus norvegicus Q62761
-
-
2.7.11.1 Rattus norvegicus Q62762
-
-
2.7.11.1 Rattus norvegicus Q62763
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.7.11.1 phosphoprotein
-
 Rattus norvegicus

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.11.1 recombinant enzyme, partial Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.1 brain
-
 Rattus norvegicus
-
2.7.11.1 heart
-
 Rattus norvegicus
-
2.7.11.1 kidney
-
 Rattus norvegicus
-
2.7.11.1 liver
-
 Rattus norvegicus
-
2.7.11.1 lung
-
 Rattus norvegicus
-
2.7.11.1 muscle
-
 Rattus norvegicus
-
2.7.11.1 testis
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.1 ATP + a protein autophosphorylation when incubated with ATP and Mg2+ Rattus norvegicus ADP + a phosphoprotein
-
 ?
2.7.11.1 ATP + casein
-
 Rattus norvegicus ADP + phosphorylated casein
-
 ?
2.7.11.1 ATP + phosvitin
-
 Rattus norvegicus ADP + ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.1 casein kinase I, gamma 1 isoform
-
 Rattus norvegicus
2.7.11.1 casein kinase I, gamma 2 isoform
-
 Rattus norvegicus
2.7.11.1 casein kinase I, gamma 3 isoform
-
 Rattus norvegicus
2.7.11.1 CK1 gamma 1
-
 Rattus norvegicus
2.7.11.1 CK1 gamma 2
-
 Rattus norvegicus
2.7.11.1 CK1 gamma 3
-
 Rattus norvegicus