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Literature summary extracted from

  • Olson, N.J.; Pearson, R.B.; Needleman, D.S.; Hurwitz, M.Y.; Kemp, B.E.; Means, A.R.
    Regulatory and structural motifs of chicken gizzard myosin light chain kinase (1990), Proc. Natl. Acad. Sci. USA, 87, 2284-2288.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.18 additional information autoregulatory domain extends from Asn780 to Arg808. The peptide Leu774 to Ser787 does not inhibit smMLCK, peptides of similar or shorter length from the pseudosubstrate region, Ser787 to Val807, are potent inhibitors Gallus gallus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.18 ATP + myosin light chain Gallus gallus
-
 ADP + phosphorylated myosin light chain
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.18 Gallus gallus P11799
-
-
2.7.11.18 Gallus gallus P11799 regulatory and structural motifs
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.18 muscle
-
 Gallus gallus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.18 ATP + myosin light chain
-
 Gallus gallus ADP + phosphorylated myosin light chain
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.18 myosin light chain kinase
-
 Gallus gallus
2.7.11.18 myosin light chain kinase, smooth muscle and non-muscle isozymes
-
 Gallus gallus