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Literature summary extracted from

  • Schulman, H.; Kuret, J.; Bennett Jefferson, A.; Nose, P.S.; Spitzer, K.H.
    Ca2+/calmodulin-dependent microtubule-associated protein 2 kinase: broad substrate specificity and multifunctional potential in diverse tissues (1985), Biochemistry, 24, 5320-5327.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.11.17 cytosol
-
 Rattus norvegicus 5829
-
2.7.11.17 cytosol
-
 Aplysia californica 5829
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.17 Ca2+ requirement Rattus norvegicus
2.7.11.17 Ca2+ requirement Aplysia californica

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.11.17 51000
-
 x * 51000 + x * 60000, phosphorylated enzyme, SDS-PAGE Rattus norvegicus
2.7.11.17 51000
-
 x * 51000 + x * 60000, phosphorylated enzyme, SDS-PAGE Aplysia californica
2.7.11.17 60000
-
 x * 51000 + x * 60000, phosphorylated enzyme, SDS-PAGE Rattus norvegicus
2.7.11.17 60000
-
 x * 51000 + x * 60000, phosphorylated enzyme, SDS-PAGE Aplysia californica
2.7.11.17 519000
-
 rat lung, gel filtration, sucrose density gradient centrifugation Rattus norvegicus
2.7.11.17 580000
-
 rat brain, gel filtration Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.17 Aplysia californica
-
 marine mollusk
-
2.7.11.17 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.11.17 heart or spleen: partial Rattus norvegicus
2.7.11.17 partial Aplysia californica

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.17 brain
-
 Rattus norvegicus
-
2.7.11.17 exocrine pancreas
-
 Rattus norvegicus
-
2.7.11.17 ganglion nerve ring Aplysia californica
-
2.7.11.17 heart
-
 Rattus norvegicus
-
2.7.11.17 lung
-
 Rattus norvegicus
-
2.7.11.17 skeletal muscle
-
 Rattus norvegicus
-
2.7.11.17 spleen
-
 Rattus norvegicus
-
2.7.11.17 testis
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.17 ATP + 40S-ribosomal protein S6 rat brain Rattus norvegicus ?
-
 ?
2.7.11.17 ATP + casein rat brain Rattus norvegicus ?
-
 ?
2.7.11.17 ATP + estrogen-receptor from calf uterus
-
 Rattus norvegicus ?
-
 ?
2.7.11.17 ATP + GABA-modulin
-
 Rattus norvegicus ?
-
 ?
2.7.11.17 ATP + glycogen synthase rat brain Rattus norvegicus ?
-
 ?
2.7.11.17 ATP + microtubule-associated protein 2
-
 Aplysia californica ADP + microtubule-associated protein 2 phosphate
-
 ?
2.7.11.17 ATP + microtubule-associated protein 2 rat brain: broad specificity Rattus norvegicus ADP + microtubule-associated protein 2 phosphate
-
 ?
2.7.11.17 ATP + microtubule-associated protein 2 not MAP-1 Rattus norvegicus ADP + microtubule-associated protein 2 phosphate
-
 ?
2.7.11.17 ATP + microtubule-associated protein tau
-
 Rattus norvegicus ?
-
 ?
2.7.11.17 ATP + myosin light chain smooth-muscle, myosin, rat brain Rattus norvegicus ?
-
 ?
2.7.11.17 ATP + myosin light chain smooth-muscle, skeletal muscle Rattus norvegicus ?
-
 ?
2.7.11.17 ATP + synapsin rat brain Rattus norvegicus ?
-
 ?
2.7.11.17 ATP + tubulin rat brain Rattus norvegicus ?
-
 ?
2.7.11.17 ATP + vimentin rat brain Rattus norvegicus ?
-
 ?
2.7.11.17 additional information cytoskeletal proteins, e.g. vinculin, filamin, fodrin or neurofilament protein Rattus norvegicus ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.11.17 ? x * 51000 + x * 60000, phosphorylated enzyme, SDS-PAGE Rattus norvegicus
2.7.11.17 ? x * 51000 + x * 60000, phosphorylated enzyme, SDS-PAGE Aplysia californica

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.11.17 30
-
 assay at Rattus norvegicus
2.7.11.17 30
-
 assay at Aplysia californica

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.11.17 Calmodulin requirement Rattus norvegicus
2.7.11.17 Calmodulin requirement Aplysia californica