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Literature summary extracted from

  • Leung, H.C.E.; Chen, Y.; Winkler, M.E.
    Regulation of substrate recognition by the MiaA tRNA prenyltransferase modification enzyme of Escherichia coli K-12 (1997), J. Biol. Chem., 272, 13073-13083.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.5.1.75 ADP competitive to DELTA2-isopentenyl diphosphate Escherichia coli
2.5.1.75 ATP competitive to DELTA2-isopentenyl diphosphate Escherichia coli

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.5.1.75 additional information
-
 additional information KM for tRNA substrates is around 3 nM Escherichia coli
2.5.1.75 0.000632
-
 DELTA2-isopentenyl diphosphate
-
 Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.75 Escherichia coli
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
2.5.1.75 dimethylallyl diphosphate + adenine37 in tRNA = diphosphate + N6-dimethylallyladenine37 in tRNA mechanism Escherichia coli
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.75 dimethylallyl diphosphate + adenine37 in tRNA
-
 Escherichia coli diphosphate + N6-dimethylallyladenine37 in tRNA
-
 ?