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Literature summary extracted from

  • Williams, D.C.
    Characterization of the multiple forms of hydroxymethylbilane synthase from rat spleen (1984), Biochem. J., 217, 675-683.
    View publication on PubMedView publication on EuropePMC

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.5.1.61 43000
-
 1 * 43000, SDS-PAGE Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.5.1.61 porphobilinogen Rattus norvegicus
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.61 Rattus norvegicus
-
 male wistar rat
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.5.1.61 erythrocyte
-
 Rattus norvegicus
-
2.5.1.61 liver
-
 Rattus norvegicus
-
2.5.1.61 spleen 5 multiple enzyme forms from spleen of phenylhydrazine-treated male rats Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.5.1.61 additional information
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.61 4 porphobilinogen in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 Rattus norvegicus uroporphyrinogen III + 4 NH3
-
 ?
2.5.1.61 4 porphobilinogen + H2O
-
 Rattus norvegicus hydroxylmethylbilane + 4 NH3
-
 ?
2.5.1.61 porphobilinogen
-
 Rattus norvegicus ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.5.1.61 monomer 1 * 43000, SDS-PAGE Rattus norvegicus

Synonyms

EC Number Synonyms Comment Organism
2.5.1.61 porphobilinogen deaminase
-
 Rattus norvegicus
2.5.1.61 uroporphyrinogen I synthetase
-
 Rattus norvegicus