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Literature summary extracted from

  • Zomer, A.W.M.; Opperdoes, F.R.; van den Bosch, H.
    Alkyl dihydroxyacetone phosphate synthase in glycosomes of Trypanosoma brucei (1995), Biochim. Biophys. Acta, 1257, 167-173.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.5.1.26
-
 Trypanosoma brucei

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.5.1.26 2-oxo-3-(phosphonooxy)propyl hexadecanoate inhibitory above 0.1 mM Trypanosoma brucei
2.5.1.26 hexadecanol inhibitory above 0.3 mM Trypanosoma brucei
2.5.1.26 NaCl 50% inhibition at 0.6 M Trypanosoma brucei

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.5.1.26 0.042
-
 hexadecanol
-
 Trypanosoma brucei
2.5.1.26 0.1
-
 Palmitoyldihydroxyacetone phosphate
-
 Trypanosoma brucei

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.5.1.26 peroxisome type-1 peroxisomal targeting signal Trypanosoma brucei 5777
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.5.1.26 68900
-
 x * 68900, deduced from gene sequence Trypanosoma brucei

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.26 Trypanosoma brucei O97157
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.26 palmitoyldihydroxyacetone phosphate + octadecanol
-
 Trypanosoma brucei palmitate + 1-O-octadecyldihydroxyacetone phosphate
-
 ?
2.5.1.26 stearoyldihydroxyacetone phosphate + hexadecanol
-
 Trypanosoma brucei stearate + 1-O-hexadecyldihydroxyacetone phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.5.1.26 ? x * 68900, deduced from gene sequence Trypanosoma brucei