EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.5.1.21 | 0.0095 | - |
farnesyl diphosphate | - |
Nicotiana tabacum |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.5.1.21 | microsome | integral membrane protein | Nicotiana tabacum | - |
- |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.5.1.21 | 47000 | - |
x * 47000, immunoblot analysis of enzyme separated by SDS-PAGE | Nicotiana tabacum |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.5.1.21 | farnesyl diphosphate + farnesyl diphosphate | Nicotiana tabacum | first pathway-specific enzyme in cholesterol biosynthesis | diphosphate + presqualene diphosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.5.1.21 | Nicotiana tabacum | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.5.1.21 | partial | Nicotiana tabacum |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.5.1.21 | cell suspension culture | - |
Nicotiana tabacum | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.5.1.21 | 0.164 | - |
- |
Nicotiana tabacum |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.5.1.21 | farnesyl diphosphate + farnesyl diphosphate | first pathway-specific enzyme in cholesterol biosynthesis | Nicotiana tabacum | diphosphate + presqualene diphosphate | - |
? | |
2.5.1.21 | farnesyl diphosphate + NAD(P)H | - |
Nicotiana tabacum | squalene + diphosphate + NAD(P)+ | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.5.1.21 | ? | x * 47000, immunoblot analysis of enzyme separated by SDS-PAGE | Nicotiana tabacum |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.5.1.21 | 35 | - |
assay at | Nicotiana tabacum |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.5.1.21 | 6 | - |
- |
Nicotiana tabacum |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.5.1.21 | NADH | preference for NADPH over NADH | Nicotiana tabacum | |
2.5.1.21 | NADPH | preference for NADPH over NADH | Nicotiana tabacum |