EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.4.2.36 | 2-mercaptoethanol | activation, together with SDS or guanidine hydrochloride | Pseudomonas aeruginosa | |
2.4.2.36 | cysteine | activation, together with SDS or guanidine hydrochloride | Pseudomonas aeruginosa | |
2.4.2.36 | dithiothreitol | enhances activity together with urea | Pseudomonas aeruginosa | |
2.4.2.36 | guanidine hydrochloride | enhances activity together with dithiothreitol, cysteine, 2-mercaptoethanol or sulfite | Pseudomonas aeruginosa | |
2.4.2.36 | additional information | exotoxin is synthesized in a catalytically inactive, proenzyme form, unfolding of the toxin molecule may cause activation | Pseudomonas aeruginosa | |
2.4.2.36 | SDS | enhances activity together with dithiothreitol, cysteine, 2-mercaptoethanol or sulfite | Pseudomonas aeruginosa | |
2.4.2.36 | sulfite | activation, together with SDS or guanidine hydrochloride | Pseudomonas aeruginosa | |
2.4.2.36 | Urea | enhances activity together with dithiothreitol | Pseudomonas aeruginosa |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.4.2.36 | extracellular | exotoxin A | Pseudomonas aeruginosa | - |
- |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.2.36 | NAD+ + elongation factor 2 | Pseudomonas aeruginosa | NAD-glycohydrolase activity without acceptor substrate | nicotinamide + ADPribose-elongation factor 2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.2.36 | Pseudomonas aeruginosa | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.4.2.36 | culture supernatant | - |
Pseudomonas aeruginosa | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.2.36 | NAD+ + elongation factor 2 | NAD-glycohydrolase activity without acceptor substrate | Pseudomonas aeruginosa | nicotinamide + ADPribose-elongation factor 2 | - |
? |