EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.4.2.15 | 2-mercaptoethanol | required for optimal activity | Oryctolagus cuniculus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.4.2.15 | PCMB | 0.2 mM, complete inhibition | Oryctolagus cuniculus | |
2.4.2.15 | Tris buffer | 0.1 M, pH 7.5, 22% inhibition | Oryctolagus cuniculus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.4.2.15 | 0.21 | - |
deoxyguanosine | - |
Oryctolagus cuniculus | |
2.4.2.15 | 0.216 | - |
guanosine | - |
Oryctolagus cuniculus | |
2.4.2.15 | 0.376 | - |
phosphate | reaction with guanosine | Oryctolagus cuniculus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.2.15 | guanosine + phosphate | Oryctolagus cuniculus | enzyme may play an important role in the utilization by bone marrow of the corresponding preformed base and nucleoside reaching this tissue via blood | guanine + D-ribose 1-phosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.2.15 | Oryctolagus cuniculus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.4.2.15 | - |
Oryctolagus cuniculus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.4.2.15 | bone marrow | - |
Oryctolagus cuniculus | - |
2.4.2.15 | intestinal mucosa | - |
Oryctolagus cuniculus | - |
2.4.2.15 | liver | - |
Oryctolagus cuniculus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.4.2.15 | 4.87 | - |
- |
Oryctolagus cuniculus |
EC Number | Storage Stability | Organism |
---|---|---|
2.4.2.15 | -10 C, stable for 1 month | Oryctolagus cuniculus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.2.15 | deoxyguanosine + phosphate | - |
Oryctolagus cuniculus | guanine + deoxyribose 1-phosphate | - |
? | |
2.4.2.15 | guanosine + phosphate | equilibrium constant is 0.019 | Oryctolagus cuniculus | guanine + D-ribose 1-phosphate | - |
r | |
2.4.2.15 | guanosine + phosphate | enzyme may play an important role in the utilization by bone marrow of the corresponding preformed base and nucleoside reaching this tissue via blood | Oryctolagus cuniculus | guanine + D-ribose 1-phosphate | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.4.2.15 | 7 | - |
phosphorolysis of deoxyguanosine | Oryctolagus cuniculus |
2.4.2.15 | 7 | 7.4 | phosphorolysis of guanosine | Oryctolagus cuniculus |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
2.4.2.15 | 5 | 8.5 | pH 5.0: about 35% of activity maximum, pH 8.5: about 45% of activity maximum | Oryctolagus cuniculus |