BRENDA - Enzyme Database show

Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis

Rongvaux, A.; Shea, R.J.; Mulks, M.H.; Gigot, D.; Urbain, J.; Leo, O.; Andris, F.; Eur. J. Immunol. 32, 3225-3234 (2002)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
2.4.2.12
pre-B-cell colony enhancing factor
Mus musculus
KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.4.2.12
0.00124
-
nicotinamide
-
Mus musculus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.4.2.12
cytoplasm
-
Mus musculus
5737
-
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.4.2.12
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate
Mus musculus
pre-B-cell colony enhancing factor
nicotinamide D-ribonucleotide + diphosphate
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.4.2.12
Mus musculus
-
identified as pre-B-cell colony-enhancing factor
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.4.2.12
lymphocyte
-
Mus musculus
-
2.4.2.12
additional information
ubiquitous in all tissues
Mus musculus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.4.2.12
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate
-
489743
Mus musculus
nicotinamide D-ribonucleotide + diphosphate
-
-
-
?
2.4.2.12
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate
pre-B-cell colony enhancing factor
489743
Mus musculus
nicotinamide D-ribonucleotide + diphosphate
-
-
-
?
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
2.4.2.12
pre-B-cell colony enhancing factor
Mus musculus
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.4.2.12
0.00124
-
nicotinamide
-
Mus musculus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.4.2.12
cytoplasm
-
Mus musculus
5737
-
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.4.2.12
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate
Mus musculus
pre-B-cell colony enhancing factor
nicotinamide D-ribonucleotide + diphosphate
-
-
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.4.2.12
lymphocyte
-
Mus musculus
-
2.4.2.12
additional information
ubiquitous in all tissues
Mus musculus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.4.2.12
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate
-
489743
Mus musculus
nicotinamide D-ribonucleotide + diphosphate
-
-
-
?
2.4.2.12
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate
pre-B-cell colony enhancing factor
489743
Mus musculus
nicotinamide D-ribonucleotide + diphosphate
-
-
-
?