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Literature summary extracted from

  • Agarwal, R.P.; Parks, R.E.
    Purine nucleoside phosphorylase from human erythrocytes. IV. Crystallization and some properties (1969), J. Biol. Chem., 244, 644-647.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.2.1 Inosine substrate activation Homo sapiens
2.4.2.1 Inosine no substrate activation Bos taurus

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.4.2.1
-
 Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.2.1 guanine
-
 Bos taurus
2.4.2.1 guanine
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.2.1 additional information
-
 additional information
-
 Homo sapiens
2.4.2.1 additional information
-
 additional information
-
 Bos taurus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.2.1 81000
-
 gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.1 Bos taurus
-
-
-
2.4.2.1 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.2.1
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.2.1 erythrocyte
-
 Homo sapiens
-
2.4.2.1 spleen
-
 Homo sapiens
-
2.4.2.1 spleen
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.1 deoxyinosine + phosphate
-
 Homo sapiens hypoxanthine + alpha-D-deoxyribose 1-phosphate
-
 r
2.4.2.1 deoxyinosine + phosphate
-
 Bos taurus hypoxanthine + alpha-D-deoxyribose 1-phosphate
-
 r
2.4.2.1 inosine + phosphate
-
 Homo sapiens hypoxanthine + alpha-D-ribose 1-phosphate
-
 ?
2.4.2.1 inosine + phosphate
-
 Bos taurus hypoxanthine + alpha-D-ribose 1-phosphate
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
2.4.2.1 57
-
 15 min, 50% inactivation Homo sapiens

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
2.4.2.1 6.2 10 5 min, stable Homo sapiens

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.4.2.1 0.005
-
 guanine
-
 Homo sapiens