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Literature summary extracted from

  • Fraser, I.H.; Mookerjea, S.
    Studies on the purification and properties of UDP-galactose glycoprotein galactosyltransferase from rat liver and serum (1976), Biochem. J., 156, 347-355.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.38 alpha-lactalbumin stimulates transfer of galactose from UDPgalactose to N-acetylgalactosamine Rattus norvegicus
2.4.1.90 alpha-lactalbumin stimulates transfer of galactose from UDPgalactose to N-acetylgalactosamine Rattus norvegicus

General Stability

EC Number General Stability Organism
2.4.1.38 more than 50% loss of activity on freezing Rattus norvegicus
2.4.1.90 more than 50% loss of activity on freezing Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.38 EDTA
-
Rattus norvegicus
2.4.1.90 EDTA
-
Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.38 0.0125
-
UDPgalactose
-
Rattus norvegicus
2.4.1.90 0.0125
-
UDPgalactose
-
Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.38 membrane
-
Rattus norvegicus 16020
-
2.4.1.38 soluble
-
Rattus norvegicus
-
-
2.4.1.90 membrane
-
Rattus norvegicus 16020
-
2.4.1.90 soluble
-
Rattus norvegicus
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.38 Mn2+ required Rattus norvegicus
2.4.1.38 Mn2+ optimal concentration: 12.5 mM Rattus norvegicus
2.4.1.90 Mn2+ required Rattus norvegicus
2.4.1.90 Mn2+ optimal concentration: 12.5 mM Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.1.38 43000
-
x * 43000, SDS-PAGE Rattus norvegicus
2.4.1.90 43000
-
x * 43000, SDS-PAGE Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.38 Rattus norvegicus
-
-
-
2.4.1.90 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.38
-
Rattus norvegicus
2.4.1.90
-
Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.38 liver
-
Rattus norvegicus
-
2.4.1.38 serum
-
Rattus norvegicus
-
2.4.1.90 liver
-
Rattus norvegicus
-
2.4.1.90 serum
-
Rattus norvegicus
-

Storage Stability

EC Number Storage Stability Organism
2.4.1.38 4°C, more than 50% loss of activity after 1 week Rattus norvegicus
2.4.1.90 4°C, more than 50% loss of activity after 1 week Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.38 UDPgalactose + degalactosylated fetuin
-
Rattus norvegicus UDP + fetuin containing beta-1,4-galactose linkages
-
?
2.4.1.38 UDPgalactose + glucose in presence of alpha-lactalbumin Rattus norvegicus lactose + UDP
-
?
2.4.1.38 UDPgalactose + N-acetylglucosamine
-
Rattus norvegicus UDP + N-acetyllactosamine
-
?
2.4.1.90 UDPgalactose + degalactosylated fetuin
-
Rattus norvegicus UDP + fetuin containing beta-1,4-galactose linkages
-
?
2.4.1.90 UDPgalactose + glucose in presence of alpha-lactalbumin Rattus norvegicus lactose + UDP
-
?
2.4.1.90 UDPgalactose + N-acetylglucosamine
-
Rattus norvegicus UDP + N-acetyllactosamine
-
?

Subunits

EC Number Subunits Comment Organism
2.4.1.38 ? x * 43000, SDS-PAGE Rattus norvegicus
2.4.1.90 ? x * 43000, SDS-PAGE Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.38 6.8
-
-
Rattus norvegicus
2.4.1.90 6.8
-
-
Rattus norvegicus