BRENDA - Enzyme Database

Specificity of GDP-Man:dolichyl-phosphate mannosyltransferase for the guanosine diphosphate esters of mannose analogues containing deoxy and deoxyfluoro substituents

McDowell, W.; Schwarz, R.T.; FEBS Lett. 243, 413-416 (1989)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.4.1.83
GDP
-
Gallus gallus
2.4.1.83
GDP-2-deoxy-D-glucose
-
Gallus gallus
2.4.1.83
GDP-3-deoxy-D-mannose
-
Gallus gallus
2.4.1.83
GDP-4-deoxy-D-mannose
-
Gallus gallus
2.4.1.83
GDP-6-deoxy-D-mannose
-
Gallus gallus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.4.1.83
microsome
-
Gallus gallus
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.4.1.83
Gallus gallus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.4.1.83
embryo
-
Gallus gallus
-
Specific Activity [micromol/min/mg]
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
2.4.1.83
0.000285
-
-
Gallus gallus
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.4.1.83
GDPmannose + dolichyl phosphate
-
489437
Gallus gallus
GDP + dolichyl D-mannosyl phosphate
-
489437
Gallus gallus
?
Ki Value [mM]
EC Number
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
2.4.1.83
0.0004
-
GDP-6-deoxy-D-mannose
-
Gallus gallus
2.4.1.83
0.001
-
GDP-3-deoxy-D-mannose
-
Gallus gallus
2.4.1.83
0.0013
-
GDP-2-deoxy-D-glucose
-
Gallus gallus
2.4.1.83
0.0031
-
GDP-4-deoxy-D-mannose
-
Gallus gallus
2.4.1.83
0.056
-
GDP
-
Gallus gallus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.4.1.83
GDP
-
Gallus gallus
2.4.1.83
GDP-2-deoxy-D-glucose
-
Gallus gallus
2.4.1.83
GDP-3-deoxy-D-mannose
-
Gallus gallus
2.4.1.83
GDP-4-deoxy-D-mannose
-
Gallus gallus
2.4.1.83
GDP-6-deoxy-D-mannose
-
Gallus gallus
Ki Value [mM] (protein specific)
EC Number
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
2.4.1.83
0.0004
-
GDP-6-deoxy-D-mannose
-
Gallus gallus
2.4.1.83
0.001
-
GDP-3-deoxy-D-mannose
-
Gallus gallus
2.4.1.83
0.0013
-
GDP-2-deoxy-D-glucose
-
Gallus gallus
2.4.1.83
0.0031
-
GDP-4-deoxy-D-mannose
-
Gallus gallus
2.4.1.83
0.056
-
GDP
-
Gallus gallus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.4.1.83
microsome
-
Gallus gallus
-
-
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.4.1.83
embryo
-
Gallus gallus
-
Specific Activity [micromol/min/mg] (protein specific)
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
2.4.1.83
0.000285
-
-
Gallus gallus
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.4.1.83
GDPmannose + dolichyl phosphate
-
489437
Gallus gallus
GDP + dolichyl D-mannosyl phosphate
-
489437
Gallus gallus
?