EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.4.1.80 | dioleoyl phosphatidylcholine | or other exogenous phospholipid, required for activity | Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.4.1.80 | Golgi membrane | - |
Rattus norvegicus | 139 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.80 | UDP-glucose + N-acylsphingosine | Rattus norvegicus | initial key enzyme in glycosphingolipid biosynthesis | UDP + D-glucosyl-N-acylsphingosine | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.1.80 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.4.1.80 | - |
Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.4.1.80 | liver | - |
Rattus norvegicus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.4.1.80 | 0.0436 | - |
purified enzyme | Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.80 | CDP-glucose + N-acylsphingosine | i.e. ceramide | Rattus norvegicus | CDP + D-glucosyl-N-acylsphingosine | i.e. glucosylceramide | ? | |
2.4.1.80 | TDP-glucose + N-acylsphingosine | i.e. ceramide | Rattus norvegicus | TDP + D-glucosyl-N-acylsphingosine | i.e. glucosylceramide | ? | |
2.4.1.80 | UDP-glucose + N-acylsphinganine | stereospecific and dependent on nature and chain length of N-acylsphinganine substrate | Rattus norvegicus | UDP + D-glucosyl-N-acylsphingosine | - |
? | |
2.4.1.80 | UDP-glucose + N-acylsphingosine | acceptor substrate specificity, overview | Rattus norvegicus | UDP + D-glucosyl-N-acylsphingosine | i.e. glucosylceramide | ? | |
2.4.1.80 | UDP-glucose + N-acylsphingosine | i.e. ceramide | Rattus norvegicus | UDP + D-glucosyl-N-acylsphingosine | i.e. glucosylceramide | ? | |
2.4.1.80 | UDP-glucose + N-acylsphingosine | stereospecific and dependent on nature and chain length of N-acylsphingosine substrate | Rattus norvegicus | UDP + D-glucosyl-N-acylsphingosine | i.e. glucosylceramide | ? | |
2.4.1.80 | UDP-glucose + N-acylsphingosine | UDP-glucose is the preferred donor substrate | Rattus norvegicus | UDP + D-glucosyl-N-acylsphingosine | i.e. glucosylceramide | ? | |
2.4.1.80 | UDP-glucose + N-acylsphingosine | initial key enzyme in glycosphingolipid biosynthesis | Rattus norvegicus | UDP + D-glucosyl-N-acylsphingosine | - |
? | |
2.4.1.80 | UDP-glucose + N-[7-(4-nitrobenzo-2-oxa-1,3-diazole)]-6-aminocaproyl-D-erythro-sphingosine | synthetic fluorescent ceramide substrate analogue for fluorescence enzyme assay | Rattus norvegicus | UDP + D-glucosyl-N-[7-(4-nitrobenzo-2-oxa-1,3-diazole)]-6-aminocaproyl-D-erythro-sphingosine | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.4.1.80 | ? | x * 60000-66000, SDS-PAGE | Rattus norvegicus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.4.1.80 | GCS | - |
Rattus norvegicus |
2.4.1.80 | UDP-Glc:ceramide glucosyltransferase | - |
Rattus norvegicus |