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Literature summary extracted from

  • Vunnam, R.R.; Radin, N.S.
    Short chain ceramides as substrates for glucocerebroside synthetase. Differences between liver and brain enzymes (1979), Biochim. Biophys. Acta, 573, 73-82.
    View publication on PubMed

General Stability

EC Number General Stability Organism
2.4.1.80 brain enzyme, half-life: 50 min at various temperatures Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.80 2-decanoylamido-3-morpholinopropiophenone 45% inhibition at 0.3 mM Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.80 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.80 brain
-
 Mus musculus
-
2.4.1.80 liver
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.80 UDP-glucose + decasphingosine
-
 Mus musculus UDP + D-glucosyl-decasphingosine
-
 ?
2.4.1.80 UDP-glucose + lauroyl amide
-
 Mus musculus UDP + D-glucosyllauroyl amide
-
 ?
2.4.1.80 UDP-glucose + N-acylsphingosine acceptor substrate specificity, overview Mus musculus UDP + D-glucosyl-N-acylsphingosine i.e. glucosylceramide ?
2.4.1.80 UDP-glucose + N-acylsphingosine i.e. ceramide Mus musculus UDP + D-glucosyl-N-acylsphingosine i.e. glucosylceramide ?
2.4.1.80 UDP-glucose + N-acylsphingosine overview: short-chain ceramide substrates Mus musculus UDP + D-glucosyl-N-acylsphingosine i.e. glucosylceramide ?
2.4.1.80 UDP-glucose + N-octanoyl sphingosine best substrate Mus musculus UDP + D-glucosyl-N-octanoyl sphingosine
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.80 7.8
-
 liver Mus musculus
2.4.1.80 8.2
-
 brain Mus musculus