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Literature summary extracted from

  • Paul, P.; Lutz, T.M.; Osborn, C.; Kyosseva, S.; Elbein, A.D.; Towbin, H.; Radominska, A.; Drake, R.R.
    Synthesis and characterization of a new class of inhibitors of membrane-associated UDP-glycosyltransferases (1993), J. Biol. Chem., 268, 12933-12938.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.62 PP55B i.e. isopropylidene derivative of 5'-O-[[(2-decanoylamino-3-phenylpropylloxycarbonyl)amino]sulfonyl]uridine, 21% inhibition at 0.2 mM Mus musculus
2.4.1.80 PP55B i.e. isopropylidene derivative of 5'-O-[[(2-decanoylamino-3-phenylpropylloxycarbonyl)amino]sulfonyl]uridine, 21% inhibition at 0.2 mM Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.62 microsome
-
 Mus musculus
-
-
2.4.1.80 microsome
-
 Mus musculus
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.62 Mus musculus
-
-
-
2.4.1.80 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.62 brain
-
 Mus musculus
-
2.4.1.62 liver
-
 Mus musculus
-
2.4.1.80 brain
-
 Mus musculus
-
2.4.1.80 liver
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.80 UDP-glucose + N-acylsphingosine i.e. ceramide Mus musculus UDP + D-glucosyl-N-acylsphingosine i.e. glucosylceramide ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.62 Gal-T2
-
 Mus musculus
2.4.1.80 GlcT
-
 Mus musculus