Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Lahav, M.; Chiu, T.H.; Lennarz, W.J.
    Studies on the biosynthesis of mannan in Micrococcus lysodeikticus. II. The enzymatic synthesis of mannosyl-l-phosphoryl-undecaprenol (1969), J. Biol. Chem., 244, 5890-5898.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.54 Cutscum activates Micrococcus luteus
2.4.1.54 Detergents activate Micrococcus luteus
2.4.1.54 Nonidet P-40 activates Micrococcus luteus
2.4.1.54 phosphatidylethanolamine activates Micrococcus luteus
2.4.1.54 phosphatidylglycerol requirement Micrococcus luteus
2.4.1.54 sodium lauryl sulfate activates Micrococcus luteus
2.4.1.54 Triton X-100 activates Micrococcus luteus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.54 GDP
-
 Micrococcus luteus
2.4.1.54 phosphatidylglycerol inhibits in excess amount Micrococcus luteus
2.4.1.54 undecaprenyl phosphate inhibits in excess amount Micrococcus luteus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.54 Ca2+ activation, can replace Mg2+ to some extent Micrococcus luteus
2.4.1.54 Mg2+ requirement Micrococcus luteus
2.4.1.54 Mg2+ optimal concentration: 67 mM Micrococcus luteus
2.4.1.54 Mn2+ activation, can replace Mg2+ to some extent Micrococcus luteus
2.4.1.54 additional information not activated by Co2+ Micrococcus luteus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.54 additional information Micrococcus luteus involved in biosynthesis of mannan ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.54 Micrococcus luteus
-
 Micrococcus lysodeikticus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.54 GDPmannose + ficaprenyl phosphate effective substrate Micrococcus luteus GDP + mannosyl-1-phosphorylficaprenol
-
 ?
2.4.1.54 GDPmannose + undecaprenyl phosphate
-
 Micrococcus luteus GDP + D-mannosyl-1-phosphoundecaprenol
-
 r
2.4.1.54 additional information involved in biosynthesis of mannan Micrococcus luteus ?
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.1.54 37
-
 assay at Micrococcus luteus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.54 6.9 7.5 0.06 M Tris-maleate buffer Micrococcus luteus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.4.1.54 6.2 8.6 about half-maximal activity at pH 6.2 and 8.6 Micrococcus luteus