Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Glaser, L.; Burger, M.M.
    The synthesis of teichoic acids. 3. GLUCOSYLATION OF POLYGLYCEROPHOSPHATE (1964), J. Biol. Chem., 239, 3187-3191.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.52 Mn2+ inhibitory in presence of optimal Mg2+-concentration Bacillus subtilis
2.4.1.52 additional information vancomycin, novobionin, crystal violet are no inhibitors Bacillus subtilis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.52 0.04
-
 UDPglucose
-
 Bacillus subtilis
2.4.1.52 0.1 2 poly(glycerophosphate) depending on chain length Bacillus subtilis

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.52 membrane
-
 Bacillus subtilis 16020
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.52 Ca2+ requirement, as active as Mg2+ Bacillus subtilis
2.4.1.52 Mg2+ requirement Bacillus subtilis
2.4.1.52 Mn2+ requirement, much less effective than Mg2+ and inhibitory in presence of optimal Mg2+ concentration Bacillus subtilis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.52 UDPglucose + poly(glycerophosphate) Bacillus subtilis
-
 UDP + alpha-D-glucosyl-poly(glycerol phosphate)
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.52 Bacillus subtilis
-
 NCTC 3610
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.52 partial Bacillus subtilis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.52 dTDP-glucose + poly(glycerophosphate)
-
 Bacillus subtilis dTDP + alpha-D-glucosyl-poly(glycerol phosphate)
-
 ?
2.4.1.52 UDP-glucose + poly(glycerophosphate)
-
 Bacillus subtilis UDP + alpha-D-glucosyl-poly(glycerol phosphate)
-
 ?
2.4.1.52 UDPglucose + poly(glycerophosphate)
-
 Bacillus subtilis UDP + alpha-D-glucosyl-poly(glycerol phosphate)
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.1.52 37
-
 assay at Bacillus subtilis

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.52 8
-
-
 Bacillus subtilis

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.4.1.52 5.5 9.5 15% of maximal activity at pH 5.5, 60% of maximal activity at pH 9.5 Bacillus subtilis