EC Number | Cloned (Comment) | Organism |
---|---|---|
2.4.1.41 | gene encoding ppGaNTase-T9 from sublingual gland is cloned, characterized, sequenced and expressed transiently in COS7 cells, gene encodes a unique 603-amino acid protein | Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.4.1.41 | membrane | - |
Mus musculus | 16020 | - |
2.4.1.41 | membrane | ppGaNTase-T9: type II integral membrane protein with a 20-amino acid transmembrane domain, a 9-amino acid cytoplasmic domain and a 94-amino acid stem region | Rattus norvegicus | 16020 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.41 | UDP-N-acetyl-D-galactosamine + polypeptide | Rattus norvegicus | diversely regulated ppGaNTase family may play a role in the various processes governing development | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + polypeptide | Mus musculus | initiation of mucin-type O-glycosylation by a family of polypeptide GalNAc-transferases, of which each has a unique function | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + polypeptide | Rattus norvegicus | initiation of mucin-type O-glycosylation by a family of polypeptide GalNAc-transferases, of which each has a unique function | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.1.41 | Mus musculus | - |
- |
- |
2.4.1.41 | Rattus norvegicus | Q925R7 | ppGaNTase-T9 | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.4.1.41 | brain | - |
Mus musculus | - |
2.4.1.41 | brain | ppGaNTase-T9, less amount | Rattus norvegicus | - |
2.4.1.41 | colon | - |
Mus musculus | - |
2.4.1.41 | colon | ppGaNTase-T9 | Rattus norvegicus | - |
2.4.1.41 | embryo | embryonic day 14.5, ppGaNTase-T9 is expressed relatively abundantly compared with ppGaNTase-T7, accumulation in brain | Mus musculus | - |
2.4.1.41 | heart | - |
Mus musculus | - |
2.4.1.41 | heart | ppGaNTase-T9, less amount | Rattus norvegicus | - |
2.4.1.41 | lung | - |
Mus musculus | - |
2.4.1.41 | lung | ppGaNTase-T9, less amount | Rattus norvegicus | - |
2.4.1.41 | ovary | - |
Mus musculus | - |
2.4.1.41 | ovary | ppGaNTase-T9 | Rattus norvegicus | - |
2.4.1.41 | small intestine | - |
Mus musculus | - |
2.4.1.41 | small intestine | ppGaNTase-T9 | Rattus norvegicus | - |
2.4.1.41 | spleen | - |
Mus musculus | - |
2.4.1.41 | spleen | ppGaNTase-T9, less amount | Rattus norvegicus | - |
2.4.1.41 | stomach | - |
Mus musculus | - |
2.4.1.41 | stomach | ppGaNTase-T9, less amount | Rattus norvegicus | - |
2.4.1.41 | sublingual gland | - |
Mus musculus | - |
2.4.1.41 | sublingual gland | ppGaNTase-T9 | Rattus norvegicus | - |
2.4.1.41 | testis | ppGaNTase-T9 | Rattus norvegicus | - |
2.4.1.41 | uterine cervix | - |
Mus musculus | - |
2.4.1.41 | uterine cervix | ppGaNTase-T9, less amount | Rattus norvegicus | - |
2.4.1.41 | uterus | - |
Mus musculus | - |
2.4.1.41 | uterus | ppGaNTase-T9, less amount | Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.41 | additional information | multiple enzyme isoforms | Mus musculus | ? | - |
? | |
2.4.1.41 | additional information | multiple enzyme isoforms | Rattus norvegicus | ? | - |
? | |
2.4.1.41 | additional information | 9 isoforms, ppGaNTase-T9 contains a 480-amino acid conserved region and shows no activity with non-glycosylated peptides | Rattus norvegicus | ? | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + GalNAc-glycosylated peptide | ppGaNTase-T9: acceptors are di- and triglycosylated MUC5AC and mono-glycosylated EA2, obtained by prior action of ppGaNTase-T1, but not the unmodified peptides, formation of a tetra-glycopeptide species from MUC5AC triglycopeptide substrate, ppGaNTase-T7 forms a hexa-glycopeptide species | Rattus norvegicus | UDP + N-acetyl-D-galactosaminyl-GalNAc-glucosylated peptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + polypeptide | - |
Mus musculus | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + polypeptide | transfer of GalNAc to a serine or threonine residue on the acceptor protein | Rattus norvegicus | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + polypeptide | diversely regulated ppGaNTase family may play a role in the various processes governing development | Rattus norvegicus | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + polypeptide | initiation of mucin-type O-glycosylation by a family of polypeptide GalNAc-transferases, of which each has a unique function | Mus musculus | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + polypeptide | initiation of mucin-type O-glycosylation by a family of polypeptide GalNAc-transferases, of which each has a unique function | Rattus norvegicus | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.4.1.41 | 37 | - |
assay at | Mus musculus |
2.4.1.41 | 37 | - |
assay at | Rattus norvegicus |