EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.4.1.41 | HIV-V3 | competitive inhibition of Muc2 glycosylation | Homo sapiens | |
2.4.1.41 | Muc2 | competitive inhibition of HIV-V3 peptide glycosylation | Homo sapiens |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.4.1.41 | additional information | - |
additional information | - |
Rattus norvegicus | |
2.4.1.41 | additional information | - |
additional information | - |
Sus scrofa | |
2.4.1.41 | additional information | - |
additional information | values for different human mucin Muc1 peptides | Homo sapiens | |
2.4.1.41 | 0.23 | - |
human mucin Muc2 peptide | - |
Homo sapiens | |
2.4.1.41 | 0.5 | - |
HIV-V3 peptide | - |
Homo sapiens |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.4.1.41 | 100000 | - |
gel filtration | Sus scrofa |
2.4.1.41 | 100000 | - |
gel filtration | Ovis sp. |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.41 | UDP-N-acetyl-D-galactosamine + polypeptide | Sus scrofa | - |
UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + polypeptide | Homo sapiens | different enzyme activities are involved in the initiation of GalNAc O-glycosylation and these are differentially expressed in cells and organs | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + polypeptide | Rattus norvegicus | different enzyme activities are involved in the initiation of GalNAc O-glycosylation and these are differentially expressed in cells and organs | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.1.41 | Homo sapiens | - |
- |
- |
2.4.1.41 | Ovis sp. | - |
- |
- |
2.4.1.41 | Rattus norvegicus | - |
male rats | - |
2.4.1.41 | Sus scrofa | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.4.1.41 | placenta enzyme, Muc2 peptide affinity chromatography separates two distinct transferase activities with overlapping specificity concerning Muc2 substrate, but which are distinguishable with respect to HIV-V3 substrate | Homo sapiens |
2.4.1.41 | submaxillary gland enzyme, 123.5fold | Ovis sp. |
2.4.1.41 | submaxillary gland enzyme, 25.4fold | Sus scrofa |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.4.1.41 | heart ventricle | - |
Rattus norvegicus | - |
2.4.1.41 | kidney | - |
Homo sapiens | - |
2.4.1.41 | kidney | expresses GalNAc-T2 | Rattus norvegicus | - |
2.4.1.41 | liver | expresses significantly more GalNAc-T2 than GalNAc-T1 | Homo sapiens | - |
2.4.1.41 | additional information | quantitative and qualitative differences in different organs | Homo sapiens | - |
2.4.1.41 | additional information | quantitative and qualitative differences in different organs | Rattus norvegicus | - |
2.4.1.41 | placenta | - |
Homo sapiens | - |
2.4.1.41 | salivary gland | - |
Rattus norvegicus | - |
2.4.1.41 | salivary gland | - |
Sus scrofa | - |
2.4.1.41 | salivary gland | - |
Ovis sp. | - |
2.4.1.41 | submaxillary gland | - |
Sus scrofa | - |
2.4.1.41 | submaxillary gland | - |
Ovis sp. | - |
2.4.1.41 | testis | - |
Rattus norvegicus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.4.1.41 | 0.09 | - |
- |
Sus scrofa |
2.4.1.41 | 0.11 | - |
- |
Ovis sp. |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.41 | additional information | different substrate specificities before and after Muc2 affinity chromatography of enzyme | Homo sapiens | ? | - |
? | |
2.4.1.41 | additional information | different substrate specificities before and after Muc2 affinity chromatography of enzyme | Sus scrofa | ? | - |
? | |
2.4.1.41 | additional information | different substrate specificities before and after Muc2 affinity chromatography of enzyme | Ovis sp. | ? | - |
? | |
2.4.1.41 | additional information | existence of multiple enzyme activities, differentially expressed in different organs, at least 2 distinct enzyme specificities | Homo sapiens | ? | - |
? | |
2.4.1.41 | additional information | existence of multiple enzyme activities, differentially expressed in different organs, at least 2 distinct enzyme specificities | Rattus norvegicus | ? | - |
? | |
2.4.1.41 | UDP-N-acetyl-alpha-D-galactosamine + human mucin Muc2 peptide | - |
Homo sapiens | ? | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + HIV-V3 peptide | submaxillary gland enzyme, low activity | Sus scrofa | UDP + N-acetyl-D-galactosaminyl-HIV-V3 peptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + HIV-V3 peptide | submaxillary gland enzyme, low activity | Ovis sp. | UDP + N-acetyl-D-galactosaminyl-HIV-V3 peptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + HIV-V3 peptide | placenta, but not liver enzyme | Homo sapiens | UDP + N-acetyl-D-galactosaminyl-HIV-V3 peptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + human chorionic gonadotropin-beta peptide | placenta enzyme | Homo sapiens | UDP + N-acetyl-D-galactosaminyl-human chorionic gonadotropin-beta peptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + human chorionic gonadotropin-beta peptide | only Ser acceptor sites, with a very low activity | Homo sapiens | UDP + N-acetyl-D-galactosaminyl-human chorionic gonadotropin-beta peptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + human chorionic gonadotropin-beta peptide | only Ser acceptor sites, with a very low activity | Sus scrofa | UDP + N-acetyl-D-galactosaminyl-human chorionic gonadotropin-beta peptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + human chorionic gonadotropin-beta peptide | only Ser acceptor sites, with a very low activity | Ovis sp. | UDP + N-acetyl-D-galactosaminyl-human chorionic gonadotropin-beta peptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + human chorionic gonadotropin-beta peptide | submaxillary gland enzyme | Sus scrofa | UDP + N-acetyl-D-galactosaminyl-human chorionic gonadotropin-beta peptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + human chorionic gonadotropin-beta peptide | submaxillary gland enzyme | Ovis sp. | UDP + N-acetyl-D-galactosaminyl-human chorionic gonadotropin-beta peptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + polypeptide | - |
Sus scrofa | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + polypeptide | acceptor: SIV3 peptide | Sus scrofa | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + polypeptide | transfer of GalNAc to a serine or threonine residue on the acceptor protein | Homo sapiens | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + polypeptide | transfer of GalNAc to a serine or threonine residue on the acceptor protein | Rattus norvegicus | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + polypeptide | transfer of GalNAc to a serine or threonine residue on the acceptor protein | Sus scrofa | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + polypeptide | transfer of GalNAc to a serine or threonine residue on the acceptor protein | Ovis sp. | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + polypeptide | acceptors: human mucin Muc1 and Muc2 peptides, human chorionic gonadotropin-beta peptide, HIV-V3 peptides | Homo sapiens | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + polypeptide | acceptors: human mucin Muc1 and Muc2 peptides, human chorionic gonadotropin-beta peptide, HIV-V3 peptides | Sus scrofa | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + polypeptide | acceptors: human mucin Muc1 and Muc2 peptides, human chorionic gonadotropin-beta peptide, HIV-V3 peptides | Ovis sp. | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + polypeptide | different enzyme activities are involved in the initiation of GalNAc O-glycosylation and these are differentially expressed in cells and organs | Homo sapiens | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? | |
2.4.1.41 | UDP-N-acetyl-D-galactosamine + polypeptide | different enzyme activities are involved in the initiation of GalNAc O-glycosylation and these are differentially expressed in cells and organs | Rattus norvegicus | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.4.1.41 | 37 | - |
assay at | Homo sapiens |
2.4.1.41 | 37 | - |
assay at | Rattus norvegicus |
2.4.1.41 | 37 | - |
assay at | Sus scrofa |