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Literature summary extracted from

  • Collins, D.C.; Jirku, H.; Layne, D.S.
    Steroid N-acetylglucosaminyl transferase. Localization and some properties of the enzyme in rabbit tissues (1968), J. Biol. Chem., 243, 2928-2933.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.39 Butanol-1
-
 Oryctolagus cuniculus
2.4.1.39 diethylstilbestrol
-
 Oryctolagus cuniculus
2.4.1.39 estrone
-
 Oryctolagus cuniculus
2.4.1.39 ethanol
-
 Oryctolagus cuniculus
2.4.1.39 eugenol i.e. 2-methoxy-4-(2-propenyl)phenol Oryctolagus cuniculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.39 0.0684
-
 UDP-N-acetylglucosamine
-
 Oryctolagus cuniculus
2.4.1.39 0.168
-
 17alpha-Estradiol-3-glucuronoside
-
 Oryctolagus cuniculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.39 microsome
-
 Oryctolagus cuniculus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.39 17alpha-estradiol-3-glucuronoside + UDP-N-acetylglucosamine Oryctolagus cuniculus
-
 UDP + 17alpha-(N-acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.39 Oryctolagus cuniculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.39 kidney
-
 Oryctolagus cuniculus
-
2.4.1.39 large intestine
-
 Oryctolagus cuniculus
-
2.4.1.39 liver
-
 Oryctolagus cuniculus
-
2.4.1.39 small intestine
-
 Oryctolagus cuniculus
-

Storage Stability

EC Number Storage Stability Organism
2.4.1.39 -10°C, half-life 25 days Oryctolagus cuniculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.39 16,17-epiestriol-3-D-glucuronoside + UDP-N-acetylglucosamine
-
 Oryctolagus cuniculus ?
-
 ?
2.4.1.39 16-epiestriol-3-D-glucuronoside + UDP-N-acetylglucosamine
-
 Oryctolagus cuniculus UDP + 16-(N-acetyl-D-glucosaminyl)-epiestriol 3-D-glucuronoside
-
 ?
2.4.1.39 17alpha-estradiol-3-D-glucuronoside + UDP-N-acetylglucosamine
-
 Oryctolagus cuniculus UDP + 17alpha-(N-acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside
-
 ?
2.4.1.39 17alpha-estradiol-3-glucuronoside + UDP-N-acetylglucosamine
-
 Oryctolagus cuniculus UDP + 17alpha-(N-acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside
-
 ?
2.4.1.39 additional information high specificity for the 17alpha-hydroxyl group on phenolic steroids which are already attached through position 3 to glucosiduronic acid, overview Oryctolagus cuniculus ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.39 8
-
-
 Oryctolagus cuniculus