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Literature summary extracted from

  • Vrielink, A.; Rueger, W.; Driessen, H.P.C.; Freemont, P.S.
    Crystal structure of the DNA modifying enzyme beta-glucosyltransferase in the presence and absence of the substrate uridine diphosphoglucose (1994), EMBO J., 13, 3413-3422.
    View publication on PubMedView publication on EuropePMC

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.4.1.27 crystal structure of the recombinant enzyme in the presence and absence of the substrate, UDPglucose Tequatrovirus T4
2.4.1.27 ternary complex between the T4 phage beta-glucosyltransferase, uridine diphosphoglucose and a DNA fragment containing an abasic site Tequatrovirus T4

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.27 UDP-alpha-D-glucose + 5-hydroxymethylcytosine containing DNA Tequatrovirus T4 the enzyme forms part of a phage DNA protection system UDP + beta-D-glucosyl-5-hydroxymethylcytosine containing DNA
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Organism

EC Number Organism UniProt Comment Textmining
2.4.1.27 Tequatrovirus T4
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.27 UDP-alpha-D-glucose + 5-hydroxymethylcytosine containing DNA
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 Tequatrovirus T4 UDP + beta-D-glucosyl-5-hydroxymethylcytosine containing DNA
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 ?
2.4.1.27 UDP-alpha-D-glucose + 5-hydroxymethylcytosine containing DNA the enzyme forms part of a phage DNA protection system Tequatrovirus T4 UDP + beta-D-glucosyl-5-hydroxymethylcytosine containing DNA
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 ?