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Literature summary extracted from

  • Bailly, P.; Piller, F.; Cartron, J.P.; Leroy, Y.; Fournet, B.
    Identification of UDP-galactose:lactose (lactosylceramide) alpha-4 and beta-3 galactosyltransferases in human kidney (1986), Biochem. Biophys. Res. Commun., 141, 84-91.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.179 EDTA
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.179 membrane
-
 Homo sapiens 16020
-
2.4.1.179 microsome
-
 Homo sapiens
-
-
2.4.1.228 microsome
-
 Homo sapiens
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.179 Mn2+
-
 Homo sapiens
2.4.1.228 Mn2+
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.228 UDP-galactose + beta-D-galactosyl-(1-4)-D-glucosylceramide Homo sapiens
-
 UDP + alpha-D-galactosyl-(1-4)-beta-D-galactosyl-(1-4)-D-glucosylceramide
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.179 Homo sapiens
-
-
-
2.4.1.228 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.179 partial Homo sapiens
2.4.1.228
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.179 kidney
-
 Homo sapiens
-
2.4.1.228 kidney frozen Homo sapiens
-

Storage Stability

EC Number Storage Stability Organism
2.4.1.179 4°C, in 20% glycerol, several weeks Homo sapiens
2.4.1.228 4°C, stable for several weeks in the presence of 20% glycerol Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.179 UDP-galactose + D-galactosyl-1,4-beta-D-glucose i.e. lactose Homo sapiens UDP + D-galactosyl-1,3-beta-D-galactosyl-1,4-beta-D-glucose
-
 ?
2.4.1.179 UDP-galactose + D-galactosyl-1,4-beta-D-glucosyl-R
-
 Homo sapiens UDP + D-galactosyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyl-R
-
 ?
2.4.1.179 UDP-galactose + lactosylceramide
-
 Homo sapiens ?
-
 ?
2.4.1.228 UDP-galactose + beta-D-galactosyl-(1-4)-D-glucosylceramide
-
 Homo sapiens UDP + alpha-D-galactosyl-(1-4)-beta-D-galactosyl-(1-4)-D-glucosylceramide
-
 ?
2.4.1.228 UDP-galactose + lactose
-
 Homo sapiens ?
-
 ?
2.4.1.228 UDP-galactose + lactosylceramide UDP-galactose is the sole sugar donor Homo sapiens UDP + globotriaosylceramide
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.1.179 37
-
 assay at Homo sapiens
2.4.1.228 37
-
 enzyme assay Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.179 6.8
-
 assay at Homo sapiens