EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.4.1.17 | 0.045 | - |
naloxone | apparent Km for UGT1B9 | Macaca fascicularis | |
2.4.1.17 | 0.048 | - |
naloxone | apparent Km for UGT1B9, second determination | Macaca fascicularis | |
2.4.1.17 | 0.05 | - |
Naltrexone | apparent Km for UGT1B9 | Macaca fascicularis | |
2.4.1.17 | 0.06 | - |
nalorphine | apparent Km for UGT1B9 | Macaca fascicularis | |
2.4.1.17 | 0.065 | - |
nalorphine | apparent Km for UGT1B9, second determination | Macaca fascicularis | |
2.4.1.17 | 0.067 | - |
Naltrexone | apparent Km for UGT1B9, second determination | Macaca fascicularis | |
2.4.1.17 | 0.156 | - |
codeine | apparent Km for UGT1B9, second determination | Macaca fascicularis | |
2.4.1.17 | 0.239 | - |
codeine | apparent Km for UGT1B9 | Macaca fascicularis | |
2.4.1.17 | 0.33 | - |
morphine | apparent Km for UGT1B9, formation of 3-glucuronide | Macaca fascicularis | |
2.4.1.17 | 0.702 | - |
oxymorphone | apparent Km for UGT1B9 | Macaca fascicularis | |
2.4.1.17 | 0.775 | - |
oxymorphone | apparent Km for UGT1B9, second determination | Macaca fascicularis | |
2.4.1.17 | 0.98 | - |
dihydromorphine | apparent Km for UGT1B9 | Macaca fascicularis | |
2.4.1.17 | 1.39 | - |
dihydromorphone | apparent Km for UGT1B9 | Macaca fascicularis |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.4.1.17 | endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.1.17 | Homo sapiens | - |
- |
- |
2.4.1.17 | Macaca fascicularis | - |
cynomolgus monkey | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.17 | androsterone + UDPglucuronate | - |
Homo sapiens | UDP + androsterone O-glucuronide | - |
? | |
2.4.1.17 | androsterone + UDPglucuronate | - |
Macaca fascicularis | UDP + androsterone O-glucuronide | - |
? | |
2.4.1.17 | borneol + UDPglucuronate | - |
Homo sapiens | UDP + borneol O-glucuronide | - |
? | |
2.4.1.17 | borneol + UDPglucuronate | other 7 monoterpenoid alcohols show substrate activity with UGT2B9 | Macaca fascicularis | UDP + borneol O-glucuronide | - |
? | |
2.4.1.17 | buprenorphine + UDPglucuronate | - |
Homo sapiens | UDP + buprenorphine O-glucuronide | - |
? | |
2.4.1.17 | buprenorphine + UDPglucuronate | - |
Macaca fascicularis | UDP + buprenorphine O-glucuronide | - |
? | |
2.4.1.17 | clofibrate + UDPglucuronate | - |
Macaca fascicularis | UDP + ? | - |
? | |
2.4.1.17 | clofibrate + UDPglucuronate | glucuronidated by UGT2B7 | Homo sapiens | UDP + ? | - |
? | |
2.4.1.17 | codeine + UDP-glucuronate | - |
Macaca fascicularis | codeine beta-D-glucuronide + UDP | - |
? | |
2.4.1.17 | dihydromorphine + UDPglucuronate | - |
Macaca fascicularis | UDP + dihydromorphine O-glucuronide | - |
? | |
2.4.1.17 | dihydromorphone + UDPglucuronate | - |
Macaca fascicularis | UDP + dihydromorphone O-glucuronide | - |
? | |
2.4.1.17 | dihydrotestosterone + UDPglucuronate | - |
Macaca fascicularis | UDP + dihydrotestosterone O-glucuronide | - |
? | |
2.4.1.17 | hyodeoxycholic acid + UDPglucuronate | - |
Homo sapiens | UDP + hyodeoxycholic acid O-glucuronide | - |
? | |
2.4.1.17 | hyodeoxycholic acid + UDPglucuronate | UGT2B9 glucuronidates hyodeoxycholate | Macaca fascicularis | UDP + hyodeoxycholic acid O-glucuronide | - |
? | |
2.4.1.17 | ibuprofen + UDPglucuronate | - |
Homo sapiens | UDP + ? | - |
? | |
2.4.1.17 | ibuprofen + UDPglucuronate | R and S isomers tested separately | Macaca fascicularis | UDP + ? | - |
? | |
2.4.1.17 | morphine + UDP-glucuronate | - |
Homo sapiens | UDP + morphine 3,6-diglucuronide | - |
? | |
2.4.1.17 | morphine + UDP-glucuronate | 3 and 6-glucuronide formation with UGT2B9, other 9 morphian opioids can act as substrates | Macaca fascicularis | UDP + morphine 3,6-diglucuronide | - |
? | |
2.4.1.17 | nalorphine + UDPglucuronate | - |
Macaca fascicularis | UDP + nalorphine O-glucuronate | - |
? | |
2.4.1.17 | naloxone + UDPglucuronate | - |
Macaca fascicularis | UDP + naloxone O-glucuronide | - |
? | |
2.4.1.17 | naltrexone + UDPglucuronate | - |
Macaca fascicularis | UDP + naltrexone O-glucuronide | - |
? | |
2.4.1.17 | oxymorphone + UDPglucuronate | - |
Macaca fascicularis | UDP + oxymorphone O-glucuronide | - |
? | |
2.4.1.17 | profen + UDPglucuronate | - |
Macaca fascicularis | UDP + ? | - |
? | |
2.4.1.17 | profen + UDPglucuronate | glucuronidated by UGT2B7 | Homo sapiens | UDP + ? | - |
? | |
2.4.1.17 | testosterone + UDPglucuronate | other 17 hydroxylated androgens tested | Macaca fascicularis | UDP + testosterone O-glucuronide | - |
? | |
2.4.1.17 | valproic acid + UDPglucuronate | - |
Macaca fascicularis | UDP + ? | - |
? | |
2.4.1.17 | valproic acid + UDPglucuronate | glucuronidated by UGT2B7 | Homo sapiens | UDP + ? | - |
? |