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Literature summary extracted from

  • Burchell, B.
    Substrate specificity and properties of uridine diphosphate glucuronyltransferase purified to apparent homogeneity from phenobarbital-treated rat liver (1978), Biochem. J., 173, 749-757.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.17 Diethylnitrosamine 10 mM, 2-3fold increase activity towards 2-aminophenol Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.17 5.4
-
 UDPglucuronic acid
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.17 microsome
-
 Rattus norvegicus
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.1.17 57000
-
 x * 57000, SDS-polyacrylamide gel electrophoresis Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.17 Rattus norvegicus
-
 Wistar strain
-
2.4.1.17 Rattus norvegicus Wistar
-
 Wistar strain
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.17 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.4.1.17 additional information
-
-
 Rattus norvegicus

Storage Stability

EC Number Storage Stability Organism
2.4.1.17 -20°C, 20% w/v glycerol, complete loss of activity Rattus norvegicus
2.4.1.17 0°C, half-life 18-20 days Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.17 1-naphthol + UDP-glucuronate
-
 Rattus norvegicus naphth-1-yl-beta-D-glucuronide + UDP
-
 ?
2.4.1.17 1-naphthol + UDP-glucuronate
-
 Rattus norvegicus Wistar naphth-1-yl-beta-D-glucuronide + UDP
-
 ?
2.4.1.17 4-nitrophenol + UDP-glucuronate
-
 Rattus norvegicus 4-nitrophenyl beta-D-glucuronide + UDP
-
 ?
2.4.1.17 4-nitrophenol + UDP-glucuronate
-
 Rattus norvegicus Wistar 4-nitrophenyl beta-D-glucuronide + UDP
-
 ?
2.4.1.17 morphine + UDP-glucuronate
-
 Rattus norvegicus UDP + morphine 3,6-diglucuronide
-
 ?
2.4.1.17 morphine + UDP-glucuronate
-
 Rattus norvegicus Wistar UDP + morphine 3,6-diglucuronide
-
 ?

Subunits

EC Number Subunits Comment Organism
2.4.1.17 ? x * 57000, SDS-polyacrylamide gel electrophoresis Rattus norvegicus
2.4.1.17 ? additional values for rat isozymes ranging from 51000 to 59000 Rattus norvegicus
2.4.1.17 ? all values determined by SDS-PAGE Rattus norvegicus

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
2.4.1.17 37
-
 inactivation in 15 min Rattus norvegicus