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Literature summary extracted from

  • Falany, C.N.; Green, M.D.; Swain, E.; Tephly, T.R.
    Substrate specificity and characterization of rat liver p-nitrophenol, 3alpha-hydroxysteroid and 17beta-hydroxysteroid UDP-glucuronosyltransferases (1986), Biochem. J., 238, 65-73.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.17 phosphatidylcholine required by purified preparations for optimal activity Rattus norvegicus
2.4.1.17 Phospholipids effect of various phospholipids Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.17 microsome
-
 Rattus norvegicus
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.1.17 50000
-
 x * 50000, 17beta-hydroxysteroid UDP-glucuronyltransferase Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.17 Rattus norvegicus
-
 Sprague-Dawley rat
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.17 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.17 17beta-hydroxy-5alpha-androstan-3-one + UDPglucuronate
-
 Rattus norvegicus UDP + 17beta-hydroxy-5alpha-androstan-3-one 17O-glucuronide
-
 ?
2.4.1.17 4-nitrophenol + UDP-glucuronate
-
 Rattus norvegicus 4-nitrophenyl beta-D-glucuronide + UDP
-
 ?
2.4.1.17 chenodeoxycholic acid + UDP-glucuronate
-
 Rattus norvegicus UDP + ?
-
 ?
2.4.1.17 etiocholanone + UDPglucuronate
-
 Rattus norvegicus UDP + etiocholanone O-glucuronide
-
 ?
2.4.1.17 lithocholic acid + UDPglucuronate
-
 Rattus norvegicus UDP + ?
-
 ?
2.4.1.17 testosterone + UDPglucuronate
-
 Rattus norvegicus UDP + testosterone O-glucuronide
-
 ?

Subunits

EC Number Subunits Comment Organism
2.4.1.17 ? 4-nitrophenol UDP-glucuronyltransferase Rattus norvegicus
2.4.1.17 ? 3alpha-hydroxysteroid UDP-glucuronyltransferase Rattus norvegicus
2.4.1.17 ? all values determined by SDS-PAGE Rattus norvegicus
2.4.1.17 ? x * 50000, 17beta-hydroxysteroid UDP-glucuronyltransferase Rattus norvegicus