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Literature summary extracted from

  • Noort, D.; Coughtrie, M.W.H.; Burchell, B.; van der Marel, G.A.; van Boom, J.H.; van der Gen, A.; Mulder, G.J.
    Inhibition of UDP-glucuronosyltransferase activity by possible transition-state analogues in rat-liver microsomes (1990), Eur. J. Biochem., 188, 309-312.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.17 2,2,2-(Triphenyl)ethyl-UDP
-
 Rattus norvegicus
2.4.1.17 2,5-Dichlorophenyl-UDP
-
 Rattus norvegicus
2.4.1.17 2,6-Dimethoxyphenyl-UDP
-
 Rattus norvegicus
2.4.1.17 2-(1-Naphthyl)ethyl-UDP
-
 Rattus norvegicus
2.4.1.17 2-(1-Naphthyl)ethyl-UMP
-
 Rattus norvegicus
2.4.1.17 2-(2-Naphthyl)ethyl-UDP
-
 Rattus norvegicus
2.4.1.17 2-(2-Naphthyl)ethyl-UMP
-
 Rattus norvegicus
2.4.1.17 2-(4-Bromophenyl)ethyl-UDP
-
 Rattus norvegicus
2.4.1.17 2-(4-Bromophenyl)ethyl-UMP
-
 Rattus norvegicus
2.4.1.17 2-(4-Nitrophenyl)ethyl-UDP
-
 Rattus norvegicus
2.4.1.17 2-Bromophenyl-UDP
-
 Rattus norvegicus
2.4.1.17 2-Chlorophenyl-UDP
-
 Rattus norvegicus
2.4.1.17 3-Methyl-2-nitrobenzyl-UDP
-
 Rattus norvegicus
2.4.1.17 4-Bromophenyl-UDP
-
 Rattus norvegicus
2.4.1.17 4-Chlorophenyl-UDP
-
 Rattus norvegicus
2.4.1.17 4-Iodophenyl-UDP
-
 Rattus norvegicus
2.4.1.17 4-Isopropylphenyl-UDP
-
 Rattus norvegicus
2.4.1.17 4-tert-Butylphenyl-UDP
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.17 microsome
-
 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.17 Rattus norvegicus
-
 Wistar strain
-
2.4.1.17 Rattus norvegicus Wistar
-
 Wistar strain
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.17
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.17 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.17 1-naphthol + UDP-glucuronate
-
 Rattus norvegicus naphth-1-yl-beta-D-glucuronide + UDP
-
 ?
2.4.1.17 1-naphthol + UDP-glucuronate
-
 Rattus norvegicus Wistar naphth-1-yl-beta-D-glucuronide + UDP
-
 ?
2.4.1.17 4-nitrophenol + UDP-glucuronate
-
 Rattus norvegicus 4-nitrophenyl beta-D-glucuronide + UDP
-
 ?
2.4.1.17 4-nitrophenol + UDP-glucuronate
-
 Rattus norvegicus Wistar 4-nitrophenyl beta-D-glucuronide + UDP
-
 ?
2.4.1.17 bilirubin + UDPglucuronate
-
 Rattus norvegicus bilirubin monoglucuronoside + bilirubin diglucuronoside + UDP
-
 ?
2.4.1.17 bilirubin + UDPglucuronate
-
 Rattus norvegicus Wistar bilirubin monoglucuronoside + bilirubin diglucuronoside + UDP
-
 ?
2.4.1.17 testosterone + UDPglucuronate
-
 Rattus norvegicus UDP + testosterone O-glucuronide
-
 ?
2.4.1.17 testosterone + UDPglucuronate
-
 Rattus norvegicus Wistar UDP + testosterone O-glucuronide
-
 ?