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Literature summary extracted from

  • Said, M.; Noort, D.; Magdalou, J.; Ziegler, J.C.; van der Marel, G.A.; van Boom, J.H.; Mulder, G.J.; Siest, G.
    Selective and potent inhibition of different hepatic UDP-glucuronosyltransferase activities by omega,omega,omega-triphenylalcohols and UDP derivatives (1992), Biochem. Biophys. Res. Commun., 187, 140-145.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.17 7,7,7-triphenylheptyl-UDP
-
 Rattus norvegicus
2.4.1.17 omega,omega,omega-triphenylalkyl-UDP derivatives e.g. 7,7,7-triphenylheptyl-UDP Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.17 microsome
-
 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.17 Rattus norvegicus
-
 Wistar strain
-
2.4.1.17 Rattus norvegicus Wistar
-
 Wistar strain
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.17 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.17 1-naphthol + UDP-glucuronate
-
 Rattus norvegicus naphth-1-yl-beta-D-glucuronide + UDP
-
 ?
2.4.1.17 1-naphthol + UDP-glucuronate
-
 Rattus norvegicus Wistar naphth-1-yl-beta-D-glucuronide + UDP
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.4.1.17 0.03
-
 7,7,7-triphenylheptyl-UDP apparent Ki for the inhibition of 1-naphthol glucuronidation Rattus norvegicus