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Literature summary extracted from

  • Jansen, P.L.M.
    The enzyme-catalyzed formation of bilirubin diglucurionide by a solubilized preparation from cat liver microsomes (1974), Biochim. Biophys. Acta, 338, 170-182.
No PubMed abstract available

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.17 0.36
-
 UDPglucuronate 0.017 mM bilirubin monoglucuronide added, at pH 6.5 Felis catus
2.4.1.17 0.44
-
 UDPglucuronate 0.016 mM bilirubin monoglucuronide added, at pH 8.1 Felis catus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.17 microsome
-
 Felis catus
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.17 Felis catus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.17 liver
-
 Felis catus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.17 bilirubin + UDPglucuronate
-
 Felis catus bilirubin monoglucuronoside + bilirubin diglucuronoside + UDP
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.17 6.5
-
 conversion of bilirubin monoglucuronide to bilirubin diglucuronide, second optimum at pH 8.1 Felis catus
2.4.1.17 8 8.8 glucuronidation of bilirubin Felis catus
2.4.1.17 8.1
-
 conversion of bilirubin monoglucuronide to bilirubin diglucuronide, second optimum at pH 6.5 Felis catus