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Literature summary extracted from

  • Takeya, A.; Hosomi, O.; Kogure, T.
    Identification and characterization of UDP-GalNAc: NeuAcalpha2-3Galbeta1-4Glc(NAc) beta 1-4(GalNAc to Gal)N-acetylgalactosaminyltransferase in human blood plasma (1987), J. Biochem., 101, 251-259.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.165 Triton X-100
-
 Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.165 ATP
-
 Homo sapiens
2.4.1.165 Triton X-100 weak Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.165 0.055
-
 UDP-N-acetylgalactosamine
-
 Homo sapiens
2.4.1.165 1.1
-
 N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide
-
 Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.165 Mn2+ requirement, Km: 16 mM Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.165 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.165 blood plasma group O Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.165 UDP-N-acetyl-D-galactosamine + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
-
 Homo sapiens UDP + N-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-acetylneuraminyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
-
 ?
2.4.1.165 UDP-N-acetyl-D-galactosamine + alpha1-acid glycoprotein
-
 Homo sapiens UDP + N-acetylgalactosaminyl-alpha1-acid glycoprotein
-
 ?
2.4.1.165 UDP-N-acetyl-D-galactosamine + asialofetuin
-
 Homo sapiens UDP + N-acetylgalactosaminylasialofetuin
-
 ?
2.4.1.165 UDP-N-acetyl-D-galactosamine + fetuin
-
 Homo sapiens UDP + N-acetylgalactosaminylfetuin
-
 ?
2.4.1.165 UDP-N-acetyl-D-galactosamine + glycophorin A weak activity Homo sapiens UDP + N-acetylgalactosaminyl glycophorin A
-
 ?
2.4.1.165 UDP-N-acetyl-D-galactosamine + NeuAcalpha(2-3)Galbeta(1-4)Glc i.e. 3'-sialyllactose Homo sapiens UDP + GalNAcbeta(1-4)(NeuAcalpha(2-3))Galbeta(1-4)Glc
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.165 7.5
-
 with fetuin as acceptor Homo sapiens

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.4.1.165 5.8 9.5 about half-maximal activity at pH 5.8 and 9.5 Homo sapiens