Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Tatsuno, K.; Yamada-Okabe, H.; Takagi, M.; Arisawa, M.; Sudoh, M.
    Properties of yeast expressed Aspergillus nidulans chitin synthase B which is essential for hyphal growth (1997), FEMS Microbiol. Lett., 149, 279-284.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.16 GlcNAc
-
 Aspergillus nidulans

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.16 expressed in Saccharomyces cerevisiae using the GAL1 promoter in a multicopy plasmid Aspergillus nidulans

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.16 Cu2+
-
 Aspergillus nidulans
2.4.1.16 EDTA
-
 Aspergillus nidulans
2.4.1.16 Polyoxin D
-
 Aspergillus nidulans
2.4.1.16 Zn2+
-
 Aspergillus nidulans

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.16 1.6
-
 UDP-GlcNAc
-
 Aspergillus nidulans

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.16 Mg2+ required for maximal activity Aspergillus nidulans

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.16 UDP-N-acetyl-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n Aspergillus nidulans chitin synthase B is essential for hyphal growth UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.16 Aspergillus nidulans
-
 chitin synthase B
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.4.1.16 proteolytic modification activated by trypsin Aspergillus nidulans

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.16 UDP-N-acetyl-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n
-
 Aspergillus nidulans UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1
-
 ?
2.4.1.16 UDP-N-acetyl-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n chitin synthase B is essential for hyphal growth Aspergillus nidulans UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.16 7.5
-
 activation by Mg2+ Aspergillus nidulans

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.4.1.16 6.5 8.5 pH 6.5: about 85% of maximal activity, pH 8.5: about 70% of maximal activity Aspergillus nidulans

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.4.1.16 0.01
-
 Polyoxin D
-
 Aspergillus nidulans