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Literature summary extracted from

  • Rast, D.M.; Bartnicki-Garcia, S.
    Effects of amphotericin B, nystatin, and other polyene antibiotics on chitin synthase (1981), Proc. Natl. Acad. Sci. USA, 78, 1233-1236.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.16 Nystatin 0.05 mM, marked stimulation Amylomyces rouxii

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.16 amphotericin noncompetitive Amylomyces rouxii
2.4.1.16 Filipin weak Amylomyces rouxii
2.4.1.16 Nystatin
-
 Amylomyces rouxii

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.16 Amylomyces rouxii
-
-
-
2.4.1.16 Amylomyces rouxii IM-80 / CCUG 22422 / CBS 416.77 / CCM F-220 / DSM 1191 / ATCC 24905
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.16 UDP-N-acetyl-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n
-
 Amylomyces rouxii UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1
-
 ?
2.4.1.16 UDP-N-acetyl-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n
-
 Amylomyces rouxii IM-80 / CCUG 22422 / CBS 416.77 / CCM F-220 / DSM 1191 / ATCC 24905 UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.4.1.16 0.13
-
 Amphotericin B
-
 Amylomyces rouxii