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Literature summary extracted from

  • Arroyo-Flores, B.L.; Rodriguez-Bonilla, J.; Villagomez-Castro, J.C.; Calvo-Mendez, C.; Flores-Carreon, A.; Lopez-Romero, E.
    Biosynthesis of glycoproteins in Candida albicans: Activity of mannosyl and glucosyl transferases (2000), Fungal Genet. Biol., 30, 127-133.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.117 Amphomycin IC50 0.04 mM Candida albicans
2.4.1.117 Ca2+ slight inhibition Candida albicans
2.4.1.117 Mn2+ slight inhibition Candida albicans
2.4.1.117 UMP
-
 Candida albicans

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.117 0.05
-
 UDP-glucose
-
 Candida albicans

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.117 Ca2+ no stimulation Candida albicans
2.4.1.117 Mg2+ Mg2+ required, not Mn2+, Ca2+ Candida albicans
2.4.1.117 Mn2+ no stimulation Candida albicans

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.117 Candida albicans
-
 strain ATCC 26555
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.117 UDP-glucose + dolichyl phosphate
-
 Candida albicans UDP + dolichyl beta-D-glucosyl phosphate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.1.117 28
-
-
 Candida albicans

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.117 7.5
-
 Tris/HCl buffer Candida albicans

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.4.1.117 0.3
-
 UMP
-
 Candida albicans

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
2.4.1.117 0.04
-
 IC50 0.04 mM Candida albicans Amphomycin