Literature summary extracted from

Lavoie, L.; Band, C.J.; Kong, M.; Bergeron, J.J.; Posner, B.I.
Regulation of glycogen synthase in rat hepatocytes. Evidence for multiple signaling pathways (1999), J. Biol. Chem., 274, 28279-28285.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
2.4.1.11	bisperoxyvanadium 1,10-phenanthroline	phosphatidylinositol 3-kinase inhibitor wortmannin and rapamycin inhibits activation	Rattus norvegicus
2.4.1.11	D-glucose	phosphatidylinositol 3-kinase inhibitor wortmannin inhibits activation	Rattus norvegicus
2.4.1.11	Insulin	phosphatidylinositol 3-kinase inhibitor wortmannin inhibits activation	Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.4.1.11	UDP-glucose + glycogen	Rattus norvegicus	-	glycogen + UDP	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.4.1.11	Rattus norvegicus	-	Sprague Dawley, rat	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.4.1.11	hepatocyte	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.4.1.11	UDP-glucose + glycogen	-	Rattus norvegicus	glycogen + UDP	-	?

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Release 2023.1 (January 2023)