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Literature summary extracted from
- Purification and properties of glycogen synthase I from skeletal muscle: two kinetic forms (1973), Biochim. Biophys. Acta, 293, 73-83.
General Stability
| EC Number | General Stability | Organism |
|---|---|---|
| 2.4.1.11 | sulfate stabilizes | Oryctolagus cuniculus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 2.4.1.11 | NaCl | above 100 mM | Oryctolagus cuniculus |  |
| 2.4.1.11 | UTP | - |
Oryctolagus cuniculus | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 2.4.1.11 | 0.05 | - |
UDP-glucose | with Na2SO4, form I | Oryctolagus cuniculus | |
| 2.4.1.11 | 0.11 | - |
UDP-glucose | without Na2SO4, form I | Oryctolagus cuniculus | |
| 2.4.1.11 | 0.27 | - |
UDP-glucose | with Na2SO4, form II | Oryctolagus cuniculus | |
| 2.4.1.11 | 0.72 | - |
UDP-glucose | without Na2SO4, form II | Oryctolagus cuniculus | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.4.1.11 | UDP-glucose + glycogen | Oryctolagus cuniculus | - |
glycogen + UDP | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 2.4.1.11 | Oryctolagus cuniculus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 2.4.1.11 | muscle | - |
Oryctolagus cuniculus | - |
| 2.4.1.11 | skeletal muscle | - |
Oryctolagus cuniculus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 2.4.1.11 | 5.2 | - |
- |
Oryctolagus cuniculus |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 2.4.1.11 | -60°C, stable for 2 months | Oryctolagus cuniculus |
| 2.4.1.11 | 4°C, stable for several days | Oryctolagus cuniculus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.4.1.11 | UDP-glucose + glycogen | - |
Oryctolagus cuniculus | glycogen + UDP | - |
? | |
Temperature Stability [°C]
| EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 2.4.1.11 | 30 | - |
stable up to 60 min | Oryctolagus cuniculus |
| 2.4.1.11 | 42 | - |
inactivation after 30 min, sulfate protects | Oryctolagus cuniculus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 2.4.1.11 | 7 | - |
synthase I | Oryctolagus cuniculus |
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Release 2023.1 (January 2023)
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