EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.4.1.11 | glucose 6-phosphate | synthase D, i.e. phosphorylated form, is glucose 6-phosphate dependent, synthase I, i.e. dephosphorylated form, is glucose 6-phosphate independent, interconversion of D and I forms and vice versa | Homo sapiens |
EC Number | General Stability | Organism |
---|---|---|
2.4.1.11 | albumin is essential during lyophilization, lyophilized enzyme is stable for years | Homo sapiens |
2.4.1.11 | dithiothreitol stabilizes | Homo sapiens |
2.4.1.11 | glucose 6-phosphate stabilizes | Homo sapiens |
2.4.1.11 | glycogen stabilizes | Homo sapiens |
2.4.1.11 | phosphate stabilizes | Homo sapiens |
2.4.1.11 | spontaneous, temperature-dependent inactivation caused by irreversible conformational changes | Homo sapiens |
2.4.1.11 | sulfate stabilizes | Homo sapiens |
2.4.1.11 | UDP stabilizes | Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.4.1.11 | 2-mercaptoethanol | high concentrations | Homo sapiens | |
2.4.1.11 | ATP | - |
Homo sapiens | |
2.4.1.11 | dithiothreitol | high concentrations | Homo sapiens | |
2.4.1.11 | ethanol | traces inactivate the enzyme | Homo sapiens |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.4.1.11 | 390000 | - |
sucrose density gradient centrifugation | Homo sapiens |
2.4.1.11 | 410000 | - |
gel filtration | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.11 | UDP-glucose + glycogen | Homo sapiens | - |
glycogen + UDP | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.1.11 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.4.1.11 | leukocyte | - |
Homo sapiens | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.4.1.11 | 21 | - |
synthase I | Homo sapiens |
EC Number | Storage Stability | Organism |
---|---|---|
2.4.1.11 | -20°C, glycogen-free or glycogen-containing enzyme, lyophilized, more than 3 years, solubilized enzyme several weeks | Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.11 | UDP-glucose + glycogen | - |
Homo sapiens | glycogen + UDP | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.4.1.11 | ? | x * 80000-85000, SDS-PAGE | Homo sapiens |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.4.1.11 | 37 | - |
- |
Homo sapiens |
EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.4.1.11 | 37 | - |
inactivation in a few h | Homo sapiens |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.4.1.11 | 6.8 | 9.2 | synthase I, presence of glucose 6-phosphate | Homo sapiens |
2.4.1.11 | 7.2 | 8 | synthase I, absence of glucose 6-phosphate | Homo sapiens |
EC Number | pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|---|
2.4.1.11 | 6.8 | 7.6 | - |
Homo sapiens |
2.4.1.11 | 7.4 | 8.4 | sensitive to small changes in pH in the presence of Mg2+ | Homo sapiens |