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Literature summary extracted from

  • Takahara, H.; Matsuda, K.
    Biosynthesis of glycogen in Neurospora crassa. Purification and properties of the UDPglucose:glycogen 4-alpha-glucosyltransferase (1978), Biochim. Biophys. Acta, 522, 363-374.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.11 glucose 6-phosphate dependent on Neurospora crassa

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.11 Co2+
-
 Neurospora crassa
2.4.1.11 Cu2+ 1 mM Neurospora crassa
2.4.1.11 Hg2+ 1 mM Neurospora crassa
2.4.1.11 iodoacetate not inhibitory Neurospora crassa
2.4.1.11 additional information not inhibitory: EDTA, iodoacetic acid, thioglycolate, trypsin and chymotrypsin decrease activity to 60% within 60 min Neurospora crassa
2.4.1.11 phenylmercuric acetate
-
 Neurospora crassa
2.4.1.11 SDS
-
 Neurospora crassa
2.4.1.11 Zn2+ 1 mM Neurospora crassa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.11 additional information
-
 additional information
-
 Neurospora crassa

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.11 Ca2+ no influence on activity Neurospora crassa
2.4.1.11 Mg2+ no influence on activity Neurospora crassa
2.4.1.11 Mn2+ no influence on activity Neurospora crassa
2.4.1.11 additional information no divalent cation requirement, no activation by Fe3+ Neurospora crassa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.1.11 270000
-
 sucrose density gradient centrifugation Neurospora crassa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.11 UDP-glucose + glycogen Neurospora crassa
-
 glycogen + UDP
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.11 Neurospora crassa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.4.1.11 6.884
-
-
 Neurospora crassa

Storage Stability

EC Number Storage Stability Organism
2.4.1.11 -85°C, stable for several months Neurospora crassa
2.4.1.11 4°C, 24 h stable Neurospora crassa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.11 UDP-glucose + glycogen
-
 Neurospora crassa glycogen + UDP
-
 ?
2.4.1.11 UDP-glucose + glycogen transfers glucose to glycogen as well as to its phosphorylase limit dextrin, but not to its beta-amylase dextrin, glucose, maltose and maltotriose are not acceptors Neurospora crassa glycogen + UDP
-
 ?

Subunits

EC Number Subunits Comment Organism
2.4.1.11 trimer 3 * 88000-90000, SDS-PAGE Neurospora crassa

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.1.11 30
-
-
 Neurospora crassa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.11 8.2 9
-
 Neurospora crassa

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
2.4.1.11 7.4 8.2
-
 Neurospora crassa