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Literature summary extracted from

  • Solling, H.
    Studies on the allosteric properties of glycogen synthase I (1979), Eur. J. Biochem., 94, 231-242.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.11 ATP
-
 Homo sapiens
2.4.1.11 Mg2+ toxic Homo sapiens
2.4.1.11 Na2SO4 high concentrations Homo sapiens
2.4.1.11 SO42-
-
 Homo sapiens
2.4.1.11 UDP 0.003-0.013 mM, competitive with UDP-glucose Homo sapiens
2.4.1.11 UMP competitive with UDP-glucose Homo sapiens
2.4.1.11 UTP competitive with UDP-glucose Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.11 0.021
-
 UDP-glucose alpha state Homo sapiens
2.4.1.11 0.081
-
 UDP-glucose under physiological conditions Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.11 Na2SO4 low concentrations Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.11 UDP-glucose + glycogen Homo sapiens
-
 glycogen + UDP
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.11 Homo sapiens
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
2.4.1.11 UDP-alpha-D-glucose + [(1->4)-alpha-D-glucosyl]n = UDP + [(1->4)-alpha-D-glucosyl]n+1 reaction mechanism Homo sapiens
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.11 leukocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.11 UDP-glucose + glycogen
-
 Homo sapiens glycogen + UDP
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.4.1.11 0.017
-
 UTP
-
 Homo sapiens
2.4.1.11 0.043
-
 UMP
-
 Homo sapiens