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Literature summary extracted from

  • Ariki, M.; Fukui, T.
    Inhibition of alpha-glucan phosphorylase by alpha-D-glucopyranosyl fluoride (1975), J. Biochem., 78, 1191-1199.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.1 1,5-gluconolactone strong inhibition of muscle isozyme a and b Oryctolagus cuniculus
2.4.1.1 alpha-D-glucopyranosyl fluoride strong inhibition of phosphorylase b, kinetics; weak inhibition Oryctolagus cuniculus
2.4.1.1 alpha-D-glucopyranosyl fluoride weak inhibition Solanum tuberosum
2.4.1.1 UDPglucose
-
 Oryctolagus cuniculus
2.4.1.1 UDPglucose
-
 Solanum tuberosum

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.1 additional information
-
 additional information kinetic data Oryctolagus cuniculus
2.4.1.1 additional information
-
 additional information kinetic data Solanum tuberosum
2.4.1.1 0.074
-
 AMP phosphorylase b Oryctolagus cuniculus
2.4.1.1 1.2
-
 glucose 1-phosphate
-
 Solanum tuberosum
2.4.1.1 3.2
-
 phosphate
-
 Solanum tuberosum
2.4.1.1 5.5
-
 glucose 1-phosphate phosphorylase b Oryctolagus cuniculus
2.4.1.1 11
-
 phosphate phosphorylase b Oryctolagus cuniculus

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.1 Oryctolagus cuniculus
-
-
-
2.4.1.1 Solanum tuberosum
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.1 muscle
-
 Oryctolagus cuniculus
-
2.4.1.1 tuber
-
 Solanum tuberosum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.1 glycogen + glucose 1-phosphate
-
 Oryctolagus cuniculus glycogen + phosphate
-
 r
2.4.1.1 glycogen + glucose 1-phosphate
-
 Solanum tuberosum glycogen + phosphate
-
 r
2.4.1.1 [(1->4)-alpha-D-glucosyl]n + phosphate
-
 Oryctolagus cuniculus [(1->4)-alpha-D-glucosyl]n-1 + alpha-D-glucose 1-phosphate
-
 r
2.4.1.1 [(1->4)-alpha-D-glucosyl]n + phosphate
-
 Solanum tuberosum [(1->4)-alpha-D-glucosyl]n-1 + alpha-D-glucose 1-phosphate
-
 r

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.4.1.1 0.44
-
 alpha-D-glucopyranosyl fluoride phosphorylase b, at 1 mM vs. glucose 1-phosphate Oryctolagus cuniculus
2.4.1.1 0.71
-
 alpha-D-glucopyranosyl fluoride phosphorylase b, at 1 mM vs. phosphate Oryctolagus cuniculus
2.4.1.1 14
-
 alpha-D-glucopyranosyl fluoride at 10 mM vs. glucose 1-phosphate Solanum tuberosum
2.4.1.1 18
-
 alpha-D-glucopyranosyl fluoride at 10 mM vs. phosphate Solanum tuberosum