Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Spearman, T.N.; Khandelwal, R.L.; Hamilton, I.R.
    Some regulatory properties of glycogen phosphorylase from Streptococcus salivarius (1973), Arch. Biochem. Biophys., 154, 306-313.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.1 5'-AMP activation Streptococcus salivarius
2.4.1.1 5'-AMP slight activation Streptococcus salivarius
2.4.1.1 5'-AMP inhibition of phosphorolysis at 2 mM and above Streptococcus salivarius
2.4.1.1 5'-AMP significant activation by synergism with NaF, glycogen as substrate, inhibition above 2 mM Streptococcus salivarius
2.4.1.1 ADP activation, in the absence of AMP Streptococcus salivarius
2.4.1.1 ADP-glucose 170% activation of glycogen synthesis in the absence of AMP and NaF, 68% inhibition in the presence of AMP and NaF Streptococcus salivarius
2.4.1.1 ATP activation Streptococcus salivarius
2.4.1.1 ATP no activation of synthesis Streptococcus salivarius
2.4.1.1 cAMP activation Streptococcus salivarius
2.4.1.1 cAMP in the absence of AMP, inhibition at 5 mM Streptococcus salivarius

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.1 ADPglucose
-
 Streptococcus salivarius
2.4.1.1 AMP above 2 mM Streptococcus salivarius
2.4.1.1 cAMP 5 mM, weak inhibition Streptococcus salivarius
2.4.1.1 D-glucose weak Streptococcus salivarius

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.1 additional information
-
 additional information
-
 Streptococcus salivarius
2.4.1.1 0.125
-
 AMP glycogen synthesis, in the presence of NaF Streptococcus salivarius
2.4.1.1 0.25
-
 AMP glycogen synthesis Streptococcus salivarius
2.4.1.1 0.49
-
 KF glycogen synthesis Streptococcus salivarius

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.1 NaF slight Streptococcus salivarius
2.4.1.1 NaF significant activation by synergism with AMP, glycogen as substrate Streptococcus salivarius

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.1 Streptococcus salivarius
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.1 (dextrin)n-1 + glucose 1-phosphate
-
 Streptococcus salivarius (dextrin)n + phosphate
-
 r
2.4.1.1 glycogen + glucose 1-phosphate glycogen from oyster Streptococcus salivarius glycogen + phosphate
-
 r
2.4.1.1 glycogen + glucose 1-phosphate glycogen from: oyster Streptococcus salivarius glycogen + phosphate
-
 r
2.4.1.1 [(1->4)-alpha-D-glucosyl]n + phosphate polyglucose primer required Streptococcus salivarius [(1->4)-alpha-D-glucosyl]n-1 + alpha-D-glucose 1-phosphate
-
 r