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Literature summary extracted from

  • Antranikian, G.; Herzberg, C.; Gottschalk, G.
    Characterization of ATP citrate lyase from Chlorobium limicola (1982), J. Bacteriol., 152, 1284-1287.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.3.8 ADP
-
 Chlorobium limicola
2.3.3.8 citrate
-
 Chlorobium limicola
2.3.3.8 CTP
-
 Chlorobium limicola
2.3.3.8 dATP weak Chlorobium limicola
2.3.3.8 DL-isocitrate
-
 Chlorobium limicola
2.3.3.8 dTTP
-
 Chlorobium limicola
2.3.3.8 Fluorocitrate
-
 Chlorobium limicola
2.3.3.8 GTP
-
 Chlorobium limicola
2.3.3.8 oxaloacetate
-
 Chlorobium limicola
2.3.3.8 tricarballylate
-
 Chlorobium limicola
2.3.3.8 UTP
-
 Chlorobium limicola

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.3.8 0.065
-
 ATP
-
 Chlorobium limicola
2.3.3.8 0.077
-
 CoA
-
 Chlorobium limicola
2.3.3.8 0.225
-
 citrate
-
 Chlorobium limicola

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.3.3.8 Co2+ can partially replace Mg2+ Chlorobium limicola
2.3.3.8 Mg2+ optimal concentration 4 mM, divalent cation required Chlorobium limicola
2.3.3.8 Mn2+ can partially replace Mg2+ Chlorobium limicola

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.3.8 240000
-
 sucrose density gradient centrifugation Chlorobium limicola

Organism

EC Number Organism UniProt Comment Textmining
2.3.3.8 Chlorobium limicola
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.3.8 partial Chlorobium limicola

Reaction

EC Number Reaction Comment Organism Reaction ID
2.3.3.8 ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA citrate cleavage is of the si-type Chlorobium limicola
a

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.3.8 additional information
-
-
 Chlorobium limicola

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.3.8 ATP + citrate + CoA
-
 Chlorobium limicola ADP + phosphate + acetyl-CoA + oxaloacetate
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.3.8 8.5
-
-
 Chlorobium limicola

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.3.3.8 0.018
-
 ADP
-
 Chlorobium limicola
2.3.3.8 0.18
-
 oxaloacetate
-
 Chlorobium limicola