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Literature summary extracted from

  • Rabin, R.; Salomon, I.I.; Bleiweis, A.S.; Carlin, J.; Ajl, S.J.
    Metabolism of ethylmalic acids by Pseudomonas aeruginosa (1968), Biochem. J., 7, 377-389.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.3.6 D-leucine weak Pseudomonas aeruginosa
2.3.3.6 L-isoleucine weak Pseudomonas aeruginosa
2.3.3.6 L-leucine 50% inhibition Pseudomonas aeruginosa

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.3.3.6 Mg2+ in the absence of Mg2+ product is formed to an extent of 64% in the complete reaction Pseudomonas aeruginosa

Organism

EC Number Organism UniProt Comment Textmining
2.3.3.6 Pseudomonas aeruginosa
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.3.6 acetyl-CoA + H2O + 2-ketoisovalerate
-
 Pseudomonas aeruginosa ?
-
 ?
2.3.3.6 acetyl-CoA + H2O + 2-ketovalerate
-
 Pseudomonas aeruginosa (R)-2-(n-propyl)-malate + CoA
-
 ?
2.3.3.6 acetyl-CoA + H2O + 2-oxobutanoate
-
 Pseudomonas aeruginosa (R)-2-ethylmalate + CoA
-
 ir
2.3.3.6 acetyl-CoA + H2O + pyruvate
-
 Pseudomonas aeruginosa ?
-
 ?
2.3.3.6 additional information not: 2-ketocaproate and 2-ketoisocaproate Pseudomonas aeruginosa ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.3.6 6.5
-
-
 Pseudomonas aeruginosa

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.3.3.6 additional information
-
 product formation doubled between pH 6.0 and 6.5, but there is a broud shoulder of activity between pH 6.5 and 7.5 Pseudomonas aeruginosa