Literature summary extracted from

  • Orlowski, M.; Meister, A.
    Enzymology of pyrrolidone carboxylic acid (1971), The Enzymes, 3rd Ed. (Boyer, P. D. , ed. ), 4, 123-151.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.3.2.9 2-aminoglutaryl-L-1-aminobutyrate
-
Cavia porcellus
4.3.2.9 2-aminoglutaryl-L-1-aminobutyrate
-
Ovis aries
4.3.2.9 2-aminoglutaryl-L-1-aminobutyrate
-
Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.3.2.9 cytoplasm
-
Homo sapiens
-
-
4.3.2.9 cytoplasm
-
Rattus norvegicus
-
-
4.3.2.9 cytoplasm
-
Ovis aries
-
-

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.48 Cavia porcellus
-
-
-
4.3.2.9 Cavia porcellus
-
guinea pig
-
4.2.1.48 Oryctolagus cuniculus
-
-
-
4.3.2.9 Ovis aries
-
-
-
4.2.1.48 Homo sapiens
-
-
-
4.3.2.9 Homo sapiens
-
-
-
4.2.1.48 Mus musculus
-
-
-
4.3.2.9 Mus musculus
-
-
-
4.2.1.48 Rattus norvegicus
-
-
-
4.3.2.9 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.3.2.9
-
Homo sapiens
4.3.2.9
-
Ovis aries

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.1.48 liver
-
Mus musculus
-
4.2.1.48 liver
-
Homo sapiens
-
4.2.1.48 liver
-
Rattus norvegicus
-
4.2.1.48 liver low activity Cavia porcellus
-
4.2.1.48 liver low activity Oryctolagus cuniculus
-
4.2.1.48 pancreas
-
Rattus norvegicus
-
4.2.1.48 skeletal muscle
-
Rattus norvegicus
-
4.2.1.48 kidney
-
Mus musculus
-
4.2.1.48 kidney
-
Homo sapiens
-
4.2.1.48 kidney
-
Rattus norvegicus
-
4.2.1.48 kidney low activity Cavia porcellus
-
4.2.1.48 kidney low activity Oryctolagus cuniculus
-
4.2.1.48 spleen
-
Rattus norvegicus
-
4.2.1.48 brain
-
Rattus norvegicus
-
4.2.1.48 testis
-
Rattus norvegicus
-
4.3.2.9 liver
-
Cavia porcellus
-
4.3.2.9 liver
-
Mus musculus
-
4.3.2.9 liver
-
Rattus norvegicus
-
4.3.2.9 lung
-
Cavia porcellus
-
4.3.2.9 lung
-
Mus musculus
-
4.3.2.9 lung
-
Homo sapiens
-
4.3.2.9 lung
-
Rattus norvegicus
-
4.3.2.9 additional information
-
Mus musculus
-
4.3.2.9 additional information
-
Homo sapiens
-
4.3.2.9 additional information
-
Rattus norvegicus
-
4.3.2.9 additional information
-
Ovis aries
-
4.3.2.9 intestine
-
Cavia porcellus
-
4.3.2.9 intestine
-
Mus musculus
-
4.3.2.9 intestine
-
Homo sapiens
-
4.3.2.9 intestine
-
Rattus norvegicus
-
4.3.2.9 skin
-
Cavia porcellus
-
4.3.2.9 skin
-
Mus musculus
-
4.3.2.9 skin
-
Homo sapiens
-

Storage Stability

EC Number Storage Stability Organism
4.3.2.9 0°C, at least 1 month Homo sapiens
4.3.2.9 0°C, at least 1 month Ovis aries

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.48 D-glutamate
-
Mus musculus 5-oxo-D-proline + H2O
-
?
4.2.1.48 D,L-glutamate
-
Mus musculus ?
-
?
4.2.1.48 D,L-gamma-hydroxyglutamate
-
Mus musculus ?
-
?
4.2.1.48 D,L-beta-hydroxyglutamate
-
Mus musculus ?
-
?
4.2.1.48 D,L-beta-methylglutamate
-
Mus musculus ?
-
?
4.2.1.48 D,L-alpha-methlylglutamate
-
Mus musculus ?
-
?
4.2.1.48 D-alpha-methylglutamate
-
Mus musculus ?
-
?
4.2.1.48 D-gamma-methylglutamate
-
Mus musculus ?
-
?
4.2.1.48 D,L-gamma-methylglutamate
-
Mus musculus ?
-
?
4.2.1.48 D,L-allo-alpha-aminotricaballylate
-
Mus musculus ?
-
?
4.2.1.48 D,L-alpha-aminotricaballylyate
-
Mus musculus ?
-
?
4.3.2.9 5-L-glutamyl-L-amino acid
-
Mus musculus 5-oxoproline + L-amino acid
-
?
4.3.2.9 5-L-glutamyl-L-amino acid
-
Rattus norvegicus 5-oxoproline + L-amino acid
-
?
4.3.2.9 5-L-glutamyl-L-amino acid no activity with L-glutamine Homo sapiens 5-oxoproline + L-amino acid
-
?
4.3.2.9 5-L-glutamyl-L-amino acid no activity with L-glutamine Ovis aries 5-oxoproline + L-amino acid
-
?
4.3.2.9 5-L-glutamyl-L-amino acid no activity with L-glutamyl-beta-alanine, L-glutamyl-3-aminoisobutyrate Homo sapiens 5-oxoproline + L-amino acid
-
?
4.3.2.9 5-L-glutamyl-L-amino acid no activity with L-glutamyl-beta-alanine, L-glutamyl-3-aminoisobutyrate Ovis aries 5-oxoproline + L-amino acid
-
?
4.3.2.9 5-L-glutamyl-L-phenylalanine poor substrate Homo sapiens 5-oxoproline + L-phenylalanine
-
?
4.3.2.9 5-L-glutamyl-L-phenylalanine poor substrate Rattus norvegicus 5-oxoproline + L-phenylalanine
-
?
4.3.2.9 5-L-glutamyl-L-phenylalanine poor substrate Ovis aries 5-oxoproline + L-phenylalanine
-
?
4.3.2.9 5-L-glutamyl-L-glutamine
-
Homo sapiens 5-oxoproline + L-glutamine
-
?
4.3.2.9 5-L-glutamyl-L-glutamine
-
Rattus norvegicus 5-oxoproline + L-glutamine
-
?
4.3.2.9 5-L-glutamyl-L-glutamine
-
Ovis aries 5-oxoproline + L-glutamine
-
?
4.3.2.9 5-L-glutamyl-L-5-L-glutamyl-L-4-nitroanilide
-
Rattus norvegicus 5-L-oxoproline + 5-L-glutamyl-L-p-nitroanilide
-
?
4.3.2.9 5-L-glutamyl-L-5-L-glutamyl-L-4-nitroanilide best substrate Homo sapiens 5-L-oxoproline + 5-L-glutamyl-L-p-nitroanilide
-
?
4.3.2.9 5-L-glutamyl-L-5-L-glutamyl-L-4-nitroanilide best substrate Ovis aries 5-L-oxoproline + 5-L-glutamyl-L-p-nitroanilide
-
?
4.3.2.9 5-L-glutamyl-L-alanine
-
Homo sapiens 5-L-oxoproline + L-alanine
-
?
4.3.2.9 5-L-glutamyl-L-alanine
-
Rattus norvegicus 5-L-oxoproline + L-alanine
-
?
4.3.2.9 5-L-glutamyl-L-alanine
-
Ovis aries 5-L-oxoproline + L-alanine
-
?
4.3.2.9 5-L-glutamyl-L-alpha-aminobutyrate
-
Mus musculus 5-L-oxoproline + L-alpha-aminobutyrate
-
?
4.3.2.9 5-L-glutamyl-L-alpha-aminobutyrate
-
Homo sapiens 5-L-oxoproline + L-alpha-aminobutyrate
-
?
4.3.2.9 5-L-glutamyl-L-alpha-aminobutyrate
-
Rattus norvegicus 5-L-oxoproline + L-alpha-aminobutyrate
-
?
4.3.2.9 5-L-glutamyl-L-alpha-aminobutyrate
-
Ovis aries 5-L-oxoproline + L-alpha-aminobutyrate
-
?
4.3.2.9 5-L-glutamyl-glycine
-
Homo sapiens 5-oxoproline + glycine
-
?
4.3.2.9 5-L-glutamyl-glycine
-
Rattus norvegicus 5-oxoproline + glycine
-
?
4.3.2.9 5-L-glutamyl-glycine
-
Ovis aries 5-oxoproline + glycine
-
?
4.3.2.9 5-L-glutamyl-S-methyl-L-cysteine
-
Homo sapiens 5-oxoproline + S-methyl-L-cysteine
-
?
4.3.2.9 5-L-glutamyl-S-methyl-L-cysteine
-
Ovis aries 5-oxoproline + S-methyl-L-cysteine
-
?
4.3.2.9 5-L-glutamyl-L-leucine
-
Homo sapiens 5-oxoproline + L-leucine
-
?
4.3.2.9 5-L-glutamyl-L-leucine
-
Rattus norvegicus 5-oxoproline + L-leucine
-
?
4.3.2.9 5-L-glutamyl-L-leucine
-
Ovis aries 5-oxoproline + L-leucine
-
?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.3.2.9 7.8 8.2 borate buffer Homo sapiens
4.3.2.9 7.8 8.2 borate buffer Ovis aries