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Literature summary extracted from

  • Bridges, R.J.; Griffith, O.W.; Meister, A.
    L-gamma-(threo-beta-methyl)glutamyl-L-alpha-aminobutyrate, a selective substrate of alpha-glutamyl cyclotransferase (1980), J. Biol. Chem., 255, 10787-10792.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.3.2.9 2-aminoglutaryl-L-1-aminobutyrate
-
 Ovis aries

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.3.2.9 5
-
 5-L-(threo-2-methyl)glutamyl-L-alpha-aminobutyrate
-
 Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
4.3.2.9 Mus musculus
-
-
-
4.3.2.9 Ovis aries
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.3.2.9 brain
-
 Ovis aries
-
4.3.2.9 kidney
-
 Mus musculus
-
4.3.2.9 liver
-
 Mus musculus
-
4.3.2.9 additional information
-
 Mus musculus
-
4.3.2.9 additional information
-
 Ovis aries
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.3.2.9 5-L-(threo-2-methyl)glutamyl-L-alpha-aminobutyrate
-
 Mus musculus ?
-
 ?
4.3.2.9 5-L-(threo-4-methyl)glutamyl-L-2-aminobutyrate
-
 Ovis aries 3-methyl-5-oxoproline + L-alpha-aminobutyrate
-
 ?
4.3.2.9 5-L-(threo-4-methyl)glutamyl-L-2-aminobutyrate model substrate, in vivo and in vitro Mus musculus 3-methyl-5-oxoproline + L-alpha-aminobutyrate
-
 ?
4.3.2.9 5-L-glutamyl-L-alpha-aminobutyrate
-
 Mus musculus 5-L-oxoproline + L-alpha-aminobutyrate
-
 ?
4.3.2.9 5-L-glutamyl-L-alpha-aminobutyrate
-
 Ovis aries 5-L-oxoproline + L-alpha-aminobutyrate
-
 ?
4.3.2.9 5-L-glutamyl-L-amino acid
-
 Mus musculus 5-oxoproline + L-amino acid i.e. 2-pyrrolidone-5-carboxylic acid ?
4.3.2.9 5-L-glutamyl-L-amino acid
-
 Ovis aries 5-oxoproline + L-amino acid i.e. 2-pyrrolidone-5-carboxylic acid ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
4.3.2.9 0.6
-
 2-aminoglutaryl-L-alpha-aminobutyrate
-
 Ovis aries