EC Number | Application | Comment | Organism |
---|---|---|---|
2.3.2.2 | medicine | bioconversion of cytotoxic and mutagenic agents to inactive 5-L-glutamyl-derivatives | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.3.2.2 | 4-nitroaniline | cytotoxic, weakly mutagenic | Rattus norvegicus | |
2.3.2.2 | 5-glutamylphenylhydrazides | no inhibition and cytotoxity | Rattus norvegicus | |
2.3.2.2 | daunomycin | cytotoxic and mutagenic | Rattus norvegicus | |
2.3.2.2 | L- or D-Serine/borate | competitive | Rattus norvegicus | |
2.3.2.2 | additional information | - |
Rattus norvegicus | |
2.3.2.2 | phenylhydrazides | cytotoxic and mutagenic | Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.2.2 | 5-D/L-glutamyl-phenylhydrazine + acceptor | Rattus norvegicus | - |
phenylhydrazine + 5-L-glutamyl-acceptor | product is cytotoxic | ir |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.2.2 | Rattus norvegicus | - |
- |
- |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
2.3.2.2 | a (5-L-glutamyl)-peptide + an amino acid = a peptide + a 5-L-glutamyl amino acid | kinetic study | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.2.2 | (5-L-glutamyl)-peptide + acceptor + H+ | concurrent reaction: hydrolase reaction with H2O as acceptor | Rattus norvegicus | peptide + 5-L-glutamyl amino acid | - |
ir | |
2.3.2.2 | (5-L-glutamyl)-peptide + acceptor + H+ | acceptor specificity, overview | Rattus norvegicus | peptide + 5-L-glutamyl amino acid | - |
ir | |
2.3.2.2 | (5-L-glutamyl)-peptide + acceptor + H+ | donor specificity, overview | Rattus norvegicus | peptide + 5-L-glutamyl amino acid | - |
ir | |
2.3.2.2 | 5-D/L-glutamyl-phenylhydrazine + acceptor | - |
Rattus norvegicus | phenylhydrazine + 5-L-glutamyl-acceptor | product is cytotoxic | ir | |
2.3.2.2 | 5-L-glutamyl-4-nitroanilide + glycylglycine | - |
Rattus norvegicus | 4-nitroaniline + 5-L-glutamylglycylglycine | 4-nitroaniline is cytotoxic | ? | |
2.3.2.2 | glutathione + daunomycin | detoxification of daunomycin by transpeptidation | Rattus norvegicus | L-cysteinylglycine + 5-L-glutamyl-daunomycin | - |
ir |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.3.2.2 | GGT | - |
Rattus norvegicus |