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Literature summary extracted from

  • Ohta, H.; Sawabu, N.; Kawakami, H.; Watanabe, H.; Ozaki, K.; Toya, D.; Hattori, N.
    Characterization of g-glutamyltranspeptidase from human hepatocellular carcinoma, compared with enzymes from normal liver and cirrhotic liver (1993), Clin. Chim. Acta, 214, 83-92.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.2.2 extracellular
-
 Homo sapiens
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.2.2 Homo sapiens
-
 6 isoforms in hepatic cellular carcinoma
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.3.2.2 glycoprotein sialoglycoprotein Homo sapiens
2.3.2.2 glycoprotein binding of concanavalin A Homo sapiens
2.3.2.2 glycoprotein binding of lentil lectin Homo sapiens

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.2.2 from normal and cirrhotic liver and 6 isoforms from serum of patients with cellular hepatic carcinoma Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.2.2 blood 6 isoforms, serum of patients with cellular hepatic carcinoma Homo sapiens
-
2.3.2.2 liver normal and cirrhotic liver Homo sapiens
-
2.3.2.2 liver hepatocellular carcinoma Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.2.2 25.6
-
 purified enzyme, normal and cirrhotic liver Homo sapiens
2.3.2.2 102.8
-
 purified enzyme of cellular hepatic carcinoma Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.2.2 (5-L-glutamyl)-peptide + acceptor + H+
-
 Homo sapiens peptide + 5-L-glutamyl amino acid
-
 ?
2.3.2.2 5-L-glutamyl-4-nitroanilide + glycylglycine
-
 Homo sapiens 4-nitroaniline + 5-L-glutamylglycylglycine
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.2.2 additional information
-
 pI: 4.2, liver enzyme Homo sapiens
2.3.2.2 additional information
-
 pIs of 6 isoforms in hepatic cellular carcinoma Homo sapiens